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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F10%3A00051416%21RIV12-MSM-14110___
rdf:type
skos:Concept n17:Vysledek
rdfs:seeAlso
http://www.jeccr.com/content/pdf/1756-9966-29-90.pdf
dcterms:description
MicroRNAs are endogenously expressed regulatory noncoding RNAs. We examined the expression levels of selected microRNAs in 38 samples of conventional renal cell carcinoma (RCC) and 10 samples of non-tumoral renal parenchyma using TaqMan real-time PCR method. We have confirmed previous observations obtained by miRNA microarray analysis using standardized real-time PCR method. For the first time, we have identified a prognostic significance of miRNA-106b, which, after validation on a larger group of patients, maybe useful as a promising biomarker in patients with RCC. MicroRNAs are endogenously expressed regulatory noncoding RNAs. We examined the expression levels of selected microRNAs in 38 samples of conventional renal cell carcinoma (RCC) and 10 samples of non-tumoral renal parenchyma using TaqMan real-time PCR method. We have confirmed previous observations obtained by miRNA microarray analysis using standardized real-time PCR method. For the first time, we have identified a prognostic significance of miRNA-106b, which, after validation on a larger group of patients, maybe useful as a promising biomarker in patients with RCC.
dcterms:title
Expression of miRNA-106b in conventional renal cell carcinoma is a potential marker for prediction of early metastasis after nephrectomy Expression of miRNA-106b in conventional renal cell carcinoma is a potential marker for prediction of early metastasis after nephrectomy
skos:prefLabel
Expression of miRNA-106b in conventional renal cell carcinoma is a potential marker for prediction of early metastasis after nephrectomy Expression of miRNA-106b in conventional renal cell carcinoma is a potential marker for prediction of early metastasis after nephrectomy
skos:notation
RIV/00216224:14110/10:00051416!RIV12-MSM-14110___
n3:aktivita
n5:I n5:P n5:Z
n3:aktivity
I, P(NS10361), Z(MZ0MOU2005)
n3:cisloPeriodika
JUL 7 2010
n3:dodaniDat
n7:2012
n3:domaciTvurceVysledku
n6:5974291 n6:7248857 n6:6522319 n6:2698374 n6:5218578 n6:2912589 n6:6760074 n6:1444409
n3:druhVysledku
n12:J
n3:duvernostUdaju
n20:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
258524
n3:idVysledku
RIV/00216224:14110/10:00051416
n3:jazykVysledku
n11:eng
n3:klicovaSlova
MicroRNA; renal cell carcinoma; miRNA-106b; nephrectomy
n3:klicoveSlovo
n9:nephrectomy n9:MicroRNA n9:miRNA-106b n9:renal%20cell%20carcinoma
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[49F95857E614]
n3:nazevZdroje
Journal of experimental & clinical cancer research
n3:obor
n21:FD
n3:pocetDomacichTvurcuVysledku
8
n3:pocetTvurcuVysledku
9
n3:projekt
n19:NS10361
n3:rokUplatneniVysledku
n7:2010
n3:svazekPeriodika
29
n3:tvurceVysledku
Vyzula, Rostislav Slabý, Ondřej Svoboda, Marek Křen, Leoš Jančovičová, Jana Michálek, Jaroslav Lakomý, Radek Poprach, Alexandr Fabian, Pavel
n3:wos
000280161800001
n3:zamer
n15:MZ0MOU2005
s:issn
1756-9966
s:numberOfPages
7
n18:doi
10.1186/1756-9966-29-90
n10:organizacniJednotka
14110