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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F10%3A00043266%21RIV11-GA0-14110___
rdf:type
skos:Concept n11:Vysledek
dcterms:description
Abstract- The effects of low-power ultrasound, the anti-cancer drug cisplatin, and their combined application were studied in two lines of human ovarian carcinoma cells, A2780 and A2780cis. Four modes of treatment were used: exposure to ultrasonic field, application of cisplatin, exposure to ultrasound followed by cisplatin, and presence of cisplatin followed by exposure to application ultrasound. Ultrasound was used at intensities of 0.5 W/cm(2) and 1.0 W/cm(2) for 10 min, cisplatin was applied at concentrations of 1 mu M and 6 mu M per cell suspension treated in A2780 and cisplatin-resistant A2780cis cells, respectively. The results of each experimental treatment were assessed by the resultant cell viability related to the viability of control cells, using a standard MTT test. It was shown that a combined effect of ultrasound and cisplatin was more effective than that of ultrasound or cisplatin alone. Abstract- The effects of low-power ultrasound, the anti-cancer drug cisplatin, and their combined application were studied in two lines of human ovarian carcinoma cells, A2780 and A2780cis. Four modes of treatment were used: exposure to ultrasonic field, application of cisplatin, exposure to ultrasound followed by cisplatin, and presence of cisplatin followed by exposure to application ultrasound. Ultrasound was used at intensities of 0.5 W/cm(2) and 1.0 W/cm(2) for 10 min, cisplatin was applied at concentrations of 1 mu M and 6 mu M per cell suspension treated in A2780 and cisplatin-resistant A2780cis cells, respectively. The results of each experimental treatment were assessed by the resultant cell viability related to the viability of control cells, using a standard MTT test. It was shown that a combined effect of ultrasound and cisplatin was more effective than that of ultrasound or cisplatin alone.
dcterms:title
Biological effects of combined ultrasound and cisplatin treatment on ovarian carcinoma cells Biological effects of combined ultrasound and cisplatin treatment on ovarian carcinoma cells
skos:prefLabel
Biological effects of combined ultrasound and cisplatin treatment on ovarian carcinoma cells Biological effects of combined ultrasound and cisplatin treatment on ovarian carcinoma cells
skos:notation
RIV/00216224:14110/10:00043266!RIV11-GA0-14110___
n5:aktivita
n16:P
n5:aktivity
P(GA305/05/2030), P(LC06077)
n5:cisloPeriodika
3
n5:dodaniDat
n12:2011
n5:domaciTvurceVysledku
n10:6443990 n10:2440024 n10:7029705 n10:9540539
n5:druhVysledku
n15:J
n5:duvernostUdaju
n13:S
n5:entitaPredkladatele
n17:predkladatel
n5:idSjednocenehoVysledku
248900
n5:idVysledku
RIV/00216224:14110/10:00043266
n5:jazykVysledku
n18:eng
n5:klicovaSlova
Carcinoma cells; Cisplatin; Ultrasound; Viability; MTT test
n5:klicoveSlovo
n8:Carcinoma%20cells n8:Cisplatin n8:MTT%20test n8:Viability n8:Ultrasound
n5:kodStatuVydavatele
NL - Nizozemsko
n5:kontrolniKodProRIV
[C9C38D821CBA]
n5:nazevZdroje
Ultrasonics
n5:obor
n14:BO
n5:pocetDomacichTvurcuVysledku
4
n5:pocetTvurcuVysledku
4
n5:projekt
n9:GA305%2F05%2F2030 n9:LC06077
n5:rokUplatneniVysledku
n12:2010
n5:svazekPeriodika
50
n5:tvurceVysledku
Škorpíková, Jiřina Slaninová, Iva Mornstein, Vojtěch Bernard, Vladan
n5:wos
000273954700004
s:issn
0041-624X
s:numberOfPages
362
n7:organizacniJednotka
14110