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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F09%3A00051164%21RIV12-MSM-14110___
rdf:type
skos:Concept n16:Vysledek
dcterms:description
We performed a retrospective, multicenter, open-label study to evaluate the efficacy Of vagus nerve stimulation (VNS) in all patients in the Czech Republic who have received this treatment for at least 5 years (n = 90). The mean last follow-up was 6.6 +/- 1.1 years (79 +/- 13 months). The median number of seizures among all patients decreased from 41.2 seizures/month in the prestimulation period to 14.9 seizures/month at 5 years follow-up visit. The mean percentage of seizure reduction was 55.9%. The responder rate in these patients is in concordance with the decrease of overall seizure frequency. At 1 year after beginning the stimulation, 44.4% of patients were responders; this percentage increased to 58.7% after 2 years. At the 5 years last follow-up 64.4% of patients were responders, 15.5% experienced >= 90% seizure reduction, and 5.5% were seizure-free. A separate analysis of patients younger than 16 years of age showed lower efficacy rates of VNS in comparison to the whole group. We performed a retrospective, multicenter, open-label study to evaluate the efficacy Of vagus nerve stimulation (VNS) in all patients in the Czech Republic who have received this treatment for at least 5 years (n = 90). The mean last follow-up was 6.6 +/- 1.1 years (79 +/- 13 months). The median number of seizures among all patients decreased from 41.2 seizures/month in the prestimulation period to 14.9 seizures/month at 5 years follow-up visit. The mean percentage of seizure reduction was 55.9%. The responder rate in these patients is in concordance with the decrease of overall seizure frequency. At 1 year after beginning the stimulation, 44.4% of patients were responders; this percentage increased to 58.7% after 2 years. At the 5 years last follow-up 64.4% of patients were responders, 15.5% experienced >= 90% seizure reduction, and 5.5% were seizure-free. A separate analysis of patients younger than 16 years of age showed lower efficacy rates of VNS in comparison to the whole group.
dcterms:title
Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years. Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years.
skos:prefLabel
Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years. Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years.
skos:notation
RIV/00216224:14110/09:00051164!RIV12-MSM-14110___
n3:aktivita
n4:I n4:S n4:P n4:V n4:Z
n3:aktivity
I, P(1D/2/16/II/04), S, V, Z(MSM0021622404)
n3:cisloPeriodika
4
n3:dodaniDat
n10:2012
n3:domaciTvurceVysledku
n7:3588998 n7:9233075 n7:3864871 n7:8132208
n3:druhVysledku
n9:J
n3:duvernostUdaju
n12:S
n3:entitaPredkladatele
n19:predkladatel
n3:idSjednocenehoVysledku
348349
n3:idVysledku
RIV/00216224:14110/09:00051164
n3:jazykVysledku
n18:eng
n3:klicovaSlova
vagus nerve stimulation; efficacy; long-term outcome; comlications
n3:klicoveSlovo
n11:long-term%20outcome n11:vagus%20nerve%20stimulation n11:comlications n11:efficacy
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[00B4EC9A577D]
n3:nazevZdroje
Seizure
n3:obor
n17:FH
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
14
n3:projekt
n20:1D%2F2%2F16%2FII%2F04
n3:rokUplatneniVysledku
n10:2009
n3:svazekPeriodika
18
n3:tvurceVysledku
Hovorka, Jiří Sebroňová, Věra Marusič, Petr Nežádal, Tomáš Rektor, Ivan Hadač, Jan Brožová, Klára Zarubova, Jana Kalina, Miroslav Ošlejšková, Hana Procházka, Tomáš Kuba, Robert Komárek, Vladimír Brázdil, Milan
n3:wos
000265465000007
n3:zamer
n8:MSM0021622404
s:issn
1059-1311
s:numberOfPages
6
n13:doi
10.1016/j.seizure.2008.10.012
n14:organizacniJednotka
14110