This HTML5 document contains 50 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n18http://localhost/temp/predkladatel/
n17http://linked.opendata.cz/resource/domain/vavai/projekt/
n6http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n15http://linked.opendata.cz/ontology/domain/vavai/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n14http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00216224%3A14110%2F08%3A00028212%21RIV09-MZ0-14110___/
n4http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n9http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n16http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n10http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n13http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n12http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n7http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F08%3A00028212%21RIV09-MZ0-14110___
rdf:type
skos:Concept n15:Vysledek
dcterms:description
Introduction and Aims: Variable degree of more or less permanent hyperglycemia characterising diabetes mellitus (DM) is causally responsible for the development of diabetic complications including diabetic nephropathy (DN). Complex dysregulation of cellular metabolism during hyperglycemia - especially accumulation of proximal glycolytic intermediates - provides substrates for certain alternative metabolic pathways (polyol, hexosamine, non-enzymatic glycation etc.) giving rise to harmful moieties (advanced glycation end-products, dicarbonyls, sorbitol, hexosamines, reactive oxygen and nitrogen species etc.). Pentose phosphate pathway (PPP) represents potentially protective mechanism in hyperglycemia since shunting of cumulated glycolytic intermediates (esp. triosephosphates) into the PPP reactions supposedly disburdens glycolysis and quantitatively limits processing of glycolytic intermediates in the alternative metabolic pathways. Transketolase (TKT), transaldolase (TALDO) and potentially TKT-like (TK Introduction and Aims: Variable degree of more or less permanent hyperglycemia characterising diabetes mellitus (DM) is causally responsible for the development of diabetic complications including diabetic nephropathy (DN). Complex dysregulation of cellular metabolism during hyperglycemia - especially accumulation of proximal glycolytic intermediates - provides substrates for certain alternative metabolic pathways (polyol, hexosamine, non-enzymatic glycation etc.) giving rise to harmful moieties (advanced glycation end-products, dicarbonyls, sorbitol, hexosamines, reactive oxygen and nitrogen species etc.). Pentose phosphate pathway (PPP) represents potentially protective mechanism in hyperglycemia since shunting of cumulated glycolytic intermediates (esp. triosephosphates) into the PPP reactions supposedly disburdens glycolysis and quantitatively limits processing of glycolytic intermediates in the alternative metabolic pathways. Transketolase (TKT), transaldolase (TALDO) and potentially TKT-like (TK Introduction and Aims: Variable degree of more or less permanent hyperglycemia characterising diabetes mellitus (DM) is causally responsible for the development of diabetic complications including diabetic nephropathy (DN). Complex dysregulation of cellular metabolism during hyperglycemia - especially accumulation of proximal glycolytic intermediates - provides substrates for certain alternative metabolic pathways (polyol, hexosamine, non-enzymatic glycation etc.) giving rise to harmful moieties (advanced glycation end-products, dicarbonyls, sorbitol, hexosamines, reactive oxygen and nitrogen species etc.). Pentose phosphate pathway (PPP) represents potentially protective mechanism in hyperglycemia since shunting of cumulated glycolytic intermediates (esp. triosephosphates) into the PPP reactions supposedly disburdens glycolysis and quantitatively limits processing of glycolytic intermediates in the alternative metabolic pathways. Transketolase (TKT), transaldolase (TALDO) and potentially TKT-like (TK
dcterms:title
Genetic variability in the pentose phosphate cycle enzymes as a treatment-independent modifier of hyperglycemia toxicity in diabetic nephropathy Genetic variability in the pentose phosphate cycle enzymes as a treatment-independent modifier of hyperglycemia toxicity in diabetic nephropathy Genetic variability in the pentose phosphate cycle enzymes as a treatment-independent modifier of hyperglycemia toxicity in diabetic nephropathy
skos:prefLabel
Genetic variability in the pentose phosphate cycle enzymes as a treatment-independent modifier of hyperglycemia toxicity in diabetic nephropathy Genetic variability in the pentose phosphate cycle enzymes as a treatment-independent modifier of hyperglycemia toxicity in diabetic nephropathy Genetic variability in the pentose phosphate cycle enzymes as a treatment-independent modifier of hyperglycemia toxicity in diabetic nephropathy
skos:notation
RIV/00216224:14110/08:00028212!RIV09-MZ0-14110___
n3:aktivita
n10:P
n3:aktivity
P(NR9443)
n3:cisloPeriodika
Suppl. 2
n3:dodaniDat
n7:2009
n3:domaciTvurceVysledku
n6:2529947 n6:5105374 n6:6108768 n6:7390343 n6:7988788 n6:8929343
n3:druhVysledku
n13:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
369130
n3:idVysledku
RIV/00216224:14110/08:00028212
n3:jazykVysledku
n16:eng
n3:klicovaSlova
diabetic nephropathy; pentose phosphate pathway; transketolase
n3:klicoveSlovo
n4:diabetic%20nephropathy n4:pentose%20phosphate%20pathway n4:transketolase
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[C23EA9EC3890]
n3:nazevZdroje
Nephrology Dialysis Transplantation
n3:obor
n12:FB
n3:pocetDomacichTvurcuVysledku
6
n3:pocetTvurcuVysledku
6
n3:projekt
n17:NR9443
n3:rokUplatneniVysledku
n7:2008
n3:svazekPeriodika
23
n3:tvurceVysledku
Olšovský, Jindřich Pácal, Lukáš Tanhäuserová, Veronika Kaňková, Kateřina Krusová, Darja Hertlová, Miluše
s:issn
0931-0509
s:numberOfPages
1
n18:organizacniJednotka
14110