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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F08%3A00027023%21RIV10-MSM-14110___
rdf:type
n8:Vysledek skos:Concept
dcterms:description
The objective of our work was to find whether the subthalamic nucleus (STN) is directly involved in cognitive activities, specifically in executive functions. Ten patients with idiopathic Parkinson's disease had P3 potentials recorded by externalized deep brain electrodes that were implanted in the STN or in its immediate vicinity. Two contacts of each electrode were positioned inside the STN according to clinical effect, perioperative microrecording, and stimulation. The P3 waves were recorded following the auditory stimulus in a standard oddball paradigm. They were compared with the P3 waves elicited from a protocol modified by a dual task with an increased demand on executive functions. The P3 potentials with a steep amplitude gradient evoked by the modified protocol were detected by the contacts in 8 of the 14 available electrodes, located either inside the STN or in its immediate vicinity. The modified protocol led to an increased latency of the P3 potential in 8 of 14 electrodes. The objective of our work was to find whether the subthalamic nucleus (STN) is directly involved in cognitive activities, specifically in executive functions. Ten patients with idiopathic Parkinson's disease had P3 potentials recorded by externalized deep brain electrodes that were implanted in the STN or in its immediate vicinity. Two contacts of each electrode were positioned inside the STN according to clinical effect, perioperative microrecording, and stimulation. The P3 waves were recorded following the auditory stimulus in a standard oddball paradigm. They were compared with the P3 waves elicited from a protocol modified by a dual task with an increased demand on executive functions. The P3 potentials with a steep amplitude gradient evoked by the modified protocol were detected by the contacts in 8 of the 14 available electrodes, located either inside the STN or in its immediate vicinity. The modified protocol led to an increased latency of the P3 potential in 8 of 14 electrodes.
dcterms:title
Participation of the subthalamic nucleus in executive functions: An intracerebral recording study. Participation of the subthalamic nucleus in executive functions: An intracerebral recording study.
skos:prefLabel
Participation of the subthalamic nucleus in executive functions: An intracerebral recording study. Participation of the subthalamic nucleus in executive functions: An intracerebral recording study.
skos:notation
RIV/00216224:14110/08:00027023!RIV10-MSM-14110___
n3:aktivita
n10:Z
n3:aktivity
Z(MSM0021622404)
n3:cisloPeriodika
4
n3:dodaniDat
n6:2010
n3:domaciTvurceVysledku
n12:1369938 n12:9233075
n3:druhVysledku
n14:J
n3:duvernostUdaju
n11:S
n3:entitaPredkladatele
n18:predkladatel
n3:idSjednocenehoVysledku
385967
n3:idVysledku
RIV/00216224:14110/08:00027023
n3:jazykVysledku
n17:eng
n3:klicovaSlova
subthalamic nucleus; deep brain stimulation; P3; executive functions
n3:klicoveSlovo
n4:executive%20functions n4:subthalamic%20nucleus n4:deep%20brain%20stimulation n4:P3
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[302011760CBE]
n3:nazevZdroje
Movement Disorders
n3:obor
n9:FH
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
3
n3:rokUplatneniVysledku
n6:2008
n3:svazekPeriodika
23
n3:tvurceVysledku
Pulkrabek, Jiří Rektor, Ivan Baláž, Marek
n3:wos
000254808000012
n3:zamer
n7:MSM0021622404
s:issn
0885-3185
s:numberOfPages
5
n15:organizacniJednotka
14110