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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F07%3A00024223%21RIV10-MZ0-14110___
rdf:type
n12:Vysledek skos:Concept
dcterms:description
Preventive transplantation of autogenous mesenchymal stem cells into iatrogenically created defect in femoral distal growth plate in rabbit prevented origination of a bone bridge and healed the physeal defect in by hyaline cartilage. Immunofluorescence examination proved that the newly created chondrocytes originated in the growth zone as a result of differentiation of implanted MSCs. Growth of the right femur in the traumatized physis was preserved after transplantation of autogenous MSCs and, compared to the left femur (with physeal defect but without transplanted MSCs), substantial shortening and valgus deformity of the bone did not occur (p=0.018). Preventive transplantation of autogenous mesenchymal stem cells into iatrogenically created defect in femoral distal growth plate in rabbit prevented origination of a bone bridge and healed the physeal defect in by hyaline cartilage. Immunofluorescence examination proved that the newly created chondrocytes originated in the growth zone as a result of differentiation of implanted MSCs. Growth of the right femur in the traumatized physis was preserved after transplantation of autogenous MSCs and, compared to the left femur (with physeal defect but without transplanted MSCs), substantial shortening and valgus deformity of the bone did not occur (p=0.018).
dcterms:title
Prevention of bone bridge formation using transplantation of the autogenous mesenchymal stem cells to physeal defects: an experimental study in rabbits. Prevention of bone bridge formation using transplantation of the autogenous mesenchymal stem cells to physeal defects: an experimental study in rabbits.
skos:prefLabel
Prevention of bone bridge formation using transplantation of the autogenous mesenchymal stem cells to physeal defects: an experimental study in rabbits. Prevention of bone bridge formation using transplantation of the autogenous mesenchymal stem cells to physeal defects: an experimental study in rabbits.
skos:notation
RIV/00216224:14110/07:00024223!RIV10-MZ0-14110___
n4:aktivita
n15:Z n15:P
n4:aktivity
P(1ET400110403), P(2B06130), P(NR8483), Z(AV0Z50390512)
n4:cisloPeriodika
1
n4:dodaniDat
n19:2010
n4:domaciTvurceVysledku
n8:5105137 n8:9306773 n8:3488349 n8:7248857 n8:3547582 n8:7072384
n4:druhVysledku
n17:J
n4:duvernostUdaju
n13:S
n4:entitaPredkladatele
n9:predkladatel
n4:idSjednocenehoVysledku
444030
n4:idVysledku
RIV/00216224:14110/07:00024223
n4:jazykVysledku
n16:eng
n4:klicovaSlova
growth plate injury; physis; growth arrest; limb deformity
n4:klicoveSlovo
n6:growth%20plate%20injury n6:limb%20deformity n6:growth%20arrest n6:physis
n4:kodStatuVydavatele
CZ - Česká republika
n4:kontrolniKodProRIV
[0CC91E5E5027]
n4:nazevZdroje
ACTA VET.
n4:obor
n5:FI
n4:pocetDomacichTvurcuVysledku
6
n4:pocetTvurcuVysledku
6
n4:projekt
n14:NR8483 n14:2B06130 n14:1ET400110403
n4:rokUplatneniVysledku
n19:2007
n4:svazekPeriodika
76
n4:tvurceVysledku
Plánka, Ladislav Nečas, Alois Gál, Petr Kecová, Alexandra Krupa, Petr Křen, Leoš
n4:wos
000248084700013
n4:zamer
n11:AV0Z50390512
s:issn
0001-7213
s:numberOfPages
11
n18:organizacniJednotka
14110