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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F07%3A00019202%21RIV10-MZ0-14110___
rdf:type
n3:Vysledek skos:Concept
dcterms:description
The 29-year-old man developed signs of secondary syphilis, which involved a rash and lymphadenopathy. He was IgM-positive (Syphilis Captia IgM, Trinity Biotech, Ireland) and his initial RPR titre was 1:128. He was treated using penicillin G procaine, 1.5 million units twice daily for 14 days and afterwards using penicillin G benzathine intramuscularly, 2.5 million units weekly within three consecutive weeks. After penicillin treatment his RPR titre decreased rapidly. In June, the titre drop from 1:128 (in the end of March) to 1:4. At the same time, the patient was IgM-negative as was assessed by the ELISA method. Serological findings suggested clinical recovery. Despite the significant decrease of RPR titres we found in his serum T. pallidum DNA by polA PCR. This means we detected the DNA of T. pallidum from serum as long as 12 weeks after treatment. The 29-year-old man developed signs of secondary syphilis, which involved a rash and lymphadenopathy. He was IgM-positive (Syphilis Captia IgM, Trinity Biotech, Ireland) and his initial RPR titre was 1:128. He was treated using penicillin G procaine, 1.5 million units twice daily for 14 days and afterwards using penicillin G benzathine intramuscularly, 2.5 million units weekly within three consecutive weeks. After penicillin treatment his RPR titre decreased rapidly. In June, the titre drop from 1:128 (in the end of March) to 1:4. At the same time, the patient was IgM-negative as was assessed by the ELISA method. Serological findings suggested clinical recovery. Despite the significant decrease of RPR titres we found in his serum T. pallidum DNA by polA PCR. This means we detected the DNA of T. pallidum from serum as long as 12 weeks after treatment.
dcterms:title
Detection of Treponema pallidum DNA from the Serum of an Adequately Treated Patient with Latent Syphilis. Detection of Treponema pallidum DNA from the Serum of an Adequately Treated Patient with Latent Syphilis.
skos:prefLabel
Detection of Treponema pallidum DNA from the Serum of an Adequately Treated Patient with Latent Syphilis. Detection of Treponema pallidum DNA from the Serum of an Adequately Treated Patient with Latent Syphilis.
skos:notation
RIV/00216224:14110/07:00019202!RIV10-MZ0-14110___
n5:aktivita
n17:S n17:P
n5:aktivity
P(NR8967), S
n5:cisloPeriodika
4
n5:dodaniDat
n12:2010
n5:domaciTvurceVysledku
n6:5287456 n6:4704339
n5:druhVysledku
n16:J
n5:duvernostUdaju
n10:S
n5:entitaPredkladatele
n13:predkladatel
n5:idSjednocenehoVysledku
416557
n5:idVysledku
RIV/00216224:14110/07:00019202
n5:jazykVysledku
n18:eng
n5:klicovaSlova
syphilis PCR T.pallidum serology
n5:klicoveSlovo
n11:syphilis%20PCR%20T.pallidum%20serology
n5:kodStatuVydavatele
SE - Švédské království
n5:kontrolniKodProRIV
[E9A656A6B6FF]
n5:nazevZdroje
Acta Dermato-Venereologica
n5:obor
n15:EE
n5:pocetDomacichTvurcuVysledku
2
n5:pocetTvurcuVysledku
2
n5:projekt
n8:NR8967
n5:rokUplatneniVysledku
n12:2007
n5:svazekPeriodika
87
n5:tvurceVysledku
Woznicová, Vladana Dvořáková Heroldová, Monika
n5:wos
000248226800024
s:issn
0001-5555
s:numberOfPages
2
n14:organizacniJednotka
14110