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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F04%3A00009924%21RIV08-MSM-14110___
rdf:type
skos:Concept n17:Vysledek
dcterms:description
The present study was designed to test a possible effect of selective agonist at cannabinoid CB2 receptor - JWH 015 (JWH) on behavioural sensitization to MET. Behavioural changes were measured in the open field test. MET and combined MET+JWH pretreatments were administered for 7 days to the mice at the doses of 2.5 mg/kg/day and 5 mg/kg/ day, respectively. On the day 8 all mice were given a "challenge dose" of MET 2.5 mg/kg to check a development of sensitization phenomenon. The sensitization to MET has not been altered in the case of use of JWH in the pretreatment. The present study was designed to test a possible effect of selective agonist at cannabinoid CB2 receptor - JWH 015 (JWH) on behavioural sensitization to MET. Behavioural changes were measured in the open field test. MET and combined MET+JWH pretreatments were administered for 7 days to the mice at the doses of 2.5 mg/kg/day and 5 mg/kg/ day, respectively. On the day 8 all mice were given a "challenge dose" of MET 2.5 mg/kg to check a development of sensitization phenomenon. The sensitization to MET has not been altered in the case of use of JWH in the pretreatment. Agonista kanabinoidních CB2 receptorů JWH 015 nepůsobí zkříženou sensitizai k účinkům metamfetaminu na lkomočně-pátrací chování myší.
dcterms:title
The impact of the cannabinoid CB2 receptor agonist JWH 015 on development of methamphetamine sensitization to locomotor/exploratory activity in mice The impact of the cannabinoid CB2 receptor agonist JWH 015 on development of methamphetamine sensitization to locomotor/exploratory activity in mice Vliv agonsity kanabinoidních CB2 receptorů, látky JWH 015, na rozvoj sensitizace k metamfetaminovému účinku na lokomočně-pátrací chování myší
skos:prefLabel
The impact of the cannabinoid CB2 receptor agonist JWH 015 on development of methamphetamine sensitization to locomotor/exploratory activity in mice Vliv agonsity kanabinoidních CB2 receptorů, látky JWH 015, na rozvoj sensitizace k metamfetaminovému účinku na lokomočně-pátrací chování myší The impact of the cannabinoid CB2 receptor agonist JWH 015 on development of methamphetamine sensitization to locomotor/exploratory activity in mice
skos:notation
RIV/00216224:14110/04:00009924!RIV08-MSM-14110___
n4:strany
54-55
n4:aktivita
n14:Z
n4:aktivity
Z(MSM 141100001)
n4:cisloPeriodika
Suppl. 1
n4:dodaniDat
n10:2008
n4:domaciTvurceVysledku
n15:3007251 n15:8841144 n15:3395197
n4:druhVysledku
n9:J
n4:duvernostUdaju
n13:S
n4:entitaPredkladatele
n7:predkladatel
n4:idSjednocenehoVysledku
567399
n4:idVysledku
RIV/00216224:14110/04:00009924
n4:jazykVysledku
n18:eng
n4:klicovaSlova
behavioural sensitization; methamphetamine; JWH-015; locomotor activity; mice
n4:klicoveSlovo
n6:locomotor%20activity n6:behavioural%20sensitization n6:JWH-015 n6:methamphetamine n6:mice
n4:kodStatuVydavatele
CZ - Česká republika
n4:kontrolniKodProRIV
[172F293DEF7D]
n4:nazevZdroje
Psychiatrie
n4:obor
n16:FR
n4:pocetDomacichTvurcuVysledku
3
n4:pocetTvurcuVysledku
3
n4:rokUplatneniVysledku
n10:2004
n4:svazekPeriodika
8
n4:tvurceVysledku
Landa, Leoš Šulcová, Alexandra Šlais, Karel
n4:zamer
n8:MSM%20141100001
s:issn
1211-7579
s:numberOfPages
2
n12:organizacniJednotka
14110