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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F04%3A00009874%21RIV09-GA0-14110___
rdf:type
n15:Vysledek skos:Concept
dcterms:description
Řada nálezů naznačuje, že oxid dusnatý (NO) hraje významnou úlohu v regulaci Th1/Th2 rovnováhy a podílí se na rozvoji alergických nemocí. Naše práce zkoumá možnou asociaci C/T záměny lokalizované 276-bp od místa ukončení translace v exonu 29 genu pro NOS1 s IgE-zprostředkovanými alergickými chorobami v české populaci Several findings suggest that nitric oxide (NO) plays a significant role in the regulation of the Th1/Th2 balance and contributes to the development of allergic diseases. Our study investigates a possible association of C/T transition located 276-bp downstream from the translation termination site in exon 29 of the human NOS1 gene with IgE-mediated allergic diseases in the Czech population. Several findings suggest that nitric oxide (NO) plays a significant role in the regulation of the Th1/Th2 balance and contributes to the development of allergic diseases. Our study investigates a possible association of C/T transition located 276-bp downstream from the translation termination site in exon 29 of the human NOS1 gene with IgE-mediated allergic diseases in the Czech population.
dcterms:title
Polymorfizmus v genu pro neuronální syntázu oxidu dusnatéhé (NOS1) a IgE-zprostředkované alergie ve středoevropské populaci Neuronal nitric oxide synthase (NOS1) gene polymorphism and IgE-mediated allergy in the Central European population Neuronal nitric oxide synthase (NOS1) gene polymorphism and IgE-mediated allergy in the Central European population
skos:prefLabel
Polymorfizmus v genu pro neuronální syntázu oxidu dusnatéhé (NOS1) a IgE-zprostředkované alergie ve středoevropské populaci Neuronal nitric oxide synthase (NOS1) gene polymorphism and IgE-mediated allergy in the Central European population Neuronal nitric oxide synthase (NOS1) gene polymorphism and IgE-mediated allergy in the Central European population
skos:notation
RIV/00216224:14110/04:00009874!RIV09-GA0-14110___
n4:aktivita
n14:Z n14:P
n4:aktivity
P(GP310/03/P045), Z(MSM 141100002)
n4:cisloPeriodika
5
n4:dodaniDat
n9:2009
n4:domaciTvurceVysledku
n10:1379097 n10:6918115 n10:1730908 n10:1993038
n4:druhVysledku
n17:J
n4:duvernostUdaju
n13:S
n4:entitaPredkladatele
n16:predkladatel
n4:idSjednocenehoVysledku
575971
n4:idVysledku
RIV/00216224:14110/04:00009874
n4:jazykVysledku
n19:eng
n4:klicovaSlova
IgE; gene; polymorphism; allergy; NOS; nitric oxide
n4:klicoveSlovo
n11:IgE n11:polymorphism n11:NOS n11:gene n11:allergy n11:nitric%20oxide
n4:kodStatuVydavatele
DK - Dánské království
n4:kontrolniKodProRIV
[98AA1C64A53B]
n4:nazevZdroje
Allergy
n4:obor
n5:EB
n4:pocetDomacichTvurcuVysledku
4
n4:pocetTvurcuVysledku
4
n4:projekt
n12:GP310%2F03%2FP045
n4:rokUplatneniVysledku
n9:2004
n4:svazekPeriodika
59
n4:tvurceVysledku
Vácha, Jiří Izakovičová-Hollá, Lydie Schüller, Marcel Bučková, Dana
n4:wos
000220703200013
n4:zamer
n18:MSM%20141100002
s:issn
0105-4538
s:numberOfPages
5
n7:organizacniJednotka
14110