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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F03%3A00011396%21RIV09-GA0-14110___
rdf:type
skos:Concept n11:Vysledek
dcterms:description
Possible UVC-protective properties of caffeic acid (CA), a plant phenolic compound with antioxidant activity, were investigated on human KF1 diploid fibroblast and A431 epidermoid carcinoma cell lines. Cell populations, untreated and treated by antioxidants (CA and á-tocopherol), were irradiated by UVC at the wavelength of 254 nm and their proliferation activity was determined by the MTT-assay. Results show a strong protective effect of CA at both concentrations used (55.5 and 165.5 ěM). This protective ability is probably based on the antioxidant and scavenging activities of CA, which seems to be more efficient than á-tocopherol in protection against cytotoxic effect caused by UVC-irradiation. Possible UVC-protective properties of caffeic acid (CA), a plant phenolic compound with antioxidant activity, were investigated on human KF1 diploid fibroblast and A431 epidermoid carcinoma cell lines. Cell populations, untreated and treated by antioxidants (CA and á-tocopherol), were irradiated by UVC at the wavelength of 254 nm and their proliferation activity was determined by the MTT-assay. Results show a strong protective effect of CA at both concentrations used (55.5 and 165.5 ěM). This protective ability is probably based on the antioxidant and scavenging activities of CA, which seems to be more efficient than á-tocopherol in protection against cytotoxic effect caused by UVC-irradiation. Možné UVC-protektivní vlastnosti kyseliny kávové (CA), rostlinné fenolické sloučeniny s antioxidační aktivitou, byly zkoumány na lidských diploidních fibroblastech KF1 a epidermoidní karcinomové linii A431.
dcterms:title
UVC-protektivní vliv kyseliny kávové na normální a transformované lidské kožní buňky in vitro. UVC-Protective Effect of Caffeic Acid on Normal and Transformated Human Skin Cells in Vitro UVC-Protective Effect of Caffeic Acid on Normal and Transformated Human Skin Cells in Vitro
skos:prefLabel
UVC-Protective Effect of Caffeic Acid on Normal and Transformated Human Skin Cells in Vitro UVC-protektivní vliv kyseliny kávové na normální a transformované lidské kožní buňky in vitro. UVC-Protective Effect of Caffeic Acid on Normal and Transformated Human Skin Cells in Vitro
skos:notation
RIV/00216224:14110/03:00011396!RIV09-GA0-14110___
n3:aktivita
n15:P
n3:aktivity
P(GA304/00/0403)
n3:cisloPeriodika
49
n3:dodaniDat
n14:2009
n3:domaciTvurceVysledku
n9:2115549 n9:1195271 n9:9637915
n3:druhVysledku
n18:J
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n12:predkladatel
n3:idSjednocenehoVysledku
632542
n3:idVysledku
RIV/00216224:14110/03:00011396
n3:jazykVysledku
n13:eng
n3:klicovaSlova
UVC; caffeic acid; UV-protective effect; alpha-tocopherol
n3:klicoveSlovo
n6:alpha-tocopherol n6:UVC n6:UV-protective%20effect n6:caffeic%20acid
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[9A865D68DFEE]
n3:nazevZdroje
Folia Biologica
n3:obor
n8:CE
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
3
n3:projekt
n16:GA304%2F00%2F0403
n3:rokUplatneniVysledku
n14:2003
n3:svazekPeriodika
2003
n3:tvurceVysledku
Neradil, Jakub Slanina, Jiří Veselská, Renata
n3:wos
000187034900004
s:issn
0015-5500
s:numberOfPages
6
n10:organizacniJednotka
14110