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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F01%3A00004338%21RIV%2F2002%2FGA0%2F141102%2FN
rdf:type
skos:Concept n9:Vysledek
dcterms:description
The objectives of the study were (i) to identify morphologically distinct stages in the cell division cycle of C. neoformans, (ii) to identify microtubular and actin components of the cytoskeleton and (iii) to investigate the effect of two cytoskeletal inhibitors, Cytochalasin D and methylbenzimidazol-2-yl carbamate (MBC), on cell proliferation and potential cell death. Both interphase and M-phase were found to be characterised each by three distinct morphological stages: mother cell, development of a sterigma-like protrusion and bud emergence, and nuclear migration into the bud and subsequent mitosis, postmitotic phase, cytokinesis and cell separation. F-actin (patches, cables and cytokinetic rings) was similar to the ascomycetous budding yeast; patches accumulated at the apex of the growing sterigma, in the bud and around the septum, but also were evenly distributed in mother cells. Cytoplasmic and spindle microtubules were similar to those in the ascomycetous fission yeast. Cytoplasmic microtubule The objectives of the study were (i) to identify morphologically distinct stages in the cell division cycle of C. neoformans, (ii) to identify microtubular and actin components of the cytoskeleton and (iii) to investigate the effect of two cytoskeletal inhibitors, Cytochalasin D and methylbenzimidazol-2-yl carbamate (MBC), on cell proliferation and potential cell death. Both interphase and M-phase were found to be characterised each by three distinct morphological stages: mother cell, development of a sterigma-like protrusion and bud emergence, and nuclear migration into the bud and subsequent mitosis, postmitotic phase, cytokinesis and cell separation. F-actin (patches, cables and cytokinetic rings) was similar to the ascomycetous budding yeast; patches accumulated at the apex of the growing sterigma, in the bud and around the septum, but also were evenly distributed in mother cells. Cytoplasmic and spindle microtubules were similar to those in the ascomycetous fission yeast. Cytoplasmic microtubule
dcterms:title
CYTOSKELETON IN THE CELL CYCLE OF CRYPTOCOCCUS NEOFORMANS AND THE EFFECTS OF CYTOSKELETAL INHIBITORS CYTOSKELETON IN THE CELL CYCLE OF CRYPTOCOCCUS NEOFORMANS AND THE EFFECTS OF CYTOSKELETAL INHIBITORS
skos:prefLabel
CYTOSKELETON IN THE CELL CYCLE OF CRYPTOCOCCUS NEOFORMANS AND THE EFFECTS OF CYTOSKELETAL INHIBITORS CYTOSKELETON IN THE CELL CYCLE OF CRYPTOCOCCUS NEOFORMANS AND THE EFFECTS OF CYTOSKELETAL INHIBITORS
skos:notation
RIV/00216224:14110/01:00004338!RIV/2002/GA0/141102/N
n3:strany
18-18
n3:aktivita
n13:P
n3:aktivity
P(GA310/00/0391)
n3:dodaniDat
n7:2002
n3:domaciTvurceVysledku
n12:3299562 n12:8883769 n12:6317804
n3:druhVysledku
n6:D
n3:duvernostUdaju
n15:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
676756
n3:idVysledku
RIV/00216224:14110/01:00004338
n3:jazykVysledku
n8:eng
n3:klicovaSlova
CYTOSKELETON IN THE CELL CYCLE OF CRYPTOCOCCUS NEOFORMANS AND THE EFFECTS OF CYTOSKELETAL INHIBITORS
n3:klicoveSlovo
n14:CYTOSKELETON%20IN%20THE%20CELL%20CYCLE%20OF%20CRYPTOCOCCUS%20NEOFORMANS%20AND%20THE%20EFFECTS%20OF%20CYTOSKELETAL%20INHIBITORS
n3:kontrolniKodProRIV
[3795A2B21D35]
n3:mistoKonaniAkce
Bratislava
n3:mistoVydani
Bratislava
n3:nazevZdroje
XXIX.Výrocná konferencia o kvasinkách, Kongresové centrum SAV Smolenice
n3:obor
n11:FP
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
5
n3:pocetUcastnikuAkce
0
n3:pocetZahranicnichUcastnikuAkce
0
n3:projekt
n20:GA310%2F00%2F0391
n3:rokUplatneniVysledku
n7:2001
n3:tvurceVysledku
Yamaguchi, Masashi Kopecká, Marie Svoboda, Augustin Gabriel, Miroslav Takeo, Kanji
n3:typAkce
n4:WRD
n3:zahajeniAkce
2001-01-01+01:00
s:numberOfPages
1
n18:hasPublisher
Chemický ústav SAV
n17:organizacniJednotka
14110