This HTML5 document contains 45 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
n6http://linked.opendata.cz/ontology/domain/vavai/riv/typAkce/
dctermshttp://purl.org/dc/terms/
n16http://purl.org/net/nknouf/ns/bibtex#
n14http://localhost/temp/predkladatel/
n19http://linked.opendata.cz/resource/domain/vavai/projekt/
n7http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n11http://linked.opendata.cz/ontology/domain/vavai/
n8http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00216224%3A14110%2F01%3A00004265%21RIV%2F2002%2FGA0%2F141102%2FN/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n5http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n4http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n17http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n12http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n20http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n13http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n18http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F01%3A00004265%21RIV%2F2002%2FGA0%2F141102%2FN
rdf:type
n11:Vysledek skos:Concept
dcterms:description
The polyphenolic compound 1, also known as cynarin, is of interest biomedically because of its hypocholesterolemic, hepatoprotective and antioxidant activity.1 The dicaffeoylquinic acids (DCQAs), in general, show a number of pharmacological actions, with the most important being anti-HIV activity. The DCQAs have recently been recognized as an important class of HIV-integrase inhibitors and, thus, prevent insertion of viral DNA into the host genome, and essential step in the replication of the virus. The DCQAs strongly and irreversibly inhibit HIV-1 integration in biochemical assays and block viral replication at non-toxic concentrations. Earlier studies2 showed that the peracetate derivatives of 3 and 4 displayed greater anti-HIV activity than the free compounds and that the activity of peracetyl-3 approaches that of AZT. Thus, there is considerable biomedical interest in the DCQAs and selected derivatives of the DCQAs. Obtaining quantities of pure 1 has been difficult. Extraction from plant ma The polyphenolic compound 1, also known as cynarin, is of interest biomedically because of its hypocholesterolemic, hepatoprotective and antioxidant activity.1 The dicaffeoylquinic acids (DCQAs), in general, show a number of pharmacological actions, with the most important being anti-HIV activity. The DCQAs have recently been recognized as an important class of HIV-integrase inhibitors and, thus, prevent insertion of viral DNA into the host genome, and essential step in the replication of the virus. The DCQAs strongly and irreversibly inhibit HIV-1 integration in biochemical assays and block viral replication at non-toxic concentrations. Earlier studies2 showed that the peracetate derivatives of 3 and 4 displayed greater anti-HIV activity than the free compounds and that the activity of peracetyl-3 approaches that of AZT. Thus, there is considerable biomedical interest in the DCQAs and selected derivatives of the DCQAs. Obtaining quantities of pure 1 has been difficult. Extraction from plant ma
dcterms:title
MASS SPECTROMETRY OF 1,3- AND 1,5-DICAFFEOYLQUINIC ACIDS MASS SPECTROMETRY OF 1,3- AND 1,5-DICAFFEOYLQUINIC ACIDS
skos:prefLabel
MASS SPECTROMETRY OF 1,3- AND 1,5-DICAFFEOYLQUINIC ACIDS MASS SPECTROMETRY OF 1,3- AND 1,5-DICAFFEOYLQUINIC ACIDS
skos:notation
RIV/00216224:14110/01:00004265!RIV/2002/GA0/141102/N
n3:strany
67
n3:aktivita
n17:P
n3:aktivity
P(GA303/00/D062)
n3:dodaniDat
n18:2002
n3:domaciTvurceVysledku
n7:2115549 n7:3682455
n3:druhVysledku
n13:D
n3:duvernostUdaju
n4:S
n3:entitaPredkladatele
n8:predkladatel
n3:idSjednocenehoVysledku
686005
n3:idVysledku
RIV/00216224:14110/01:00004265
n3:jazykVysledku
n12:eng
n3:klicovaSlova
mass spectrometry, isomers, dicaffeoylquinic acids
n3:klicoveSlovo
n5:mass%20spectrometry n5:isomers n5:dicaffeoylquinic%20acids
n3:kontrolniKodProRIV
[00EC00B9572F]
n3:mistoKonaniAkce
Chicago
n3:mistoVydani
Chicago
n3:nazevZdroje
49th American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics
n3:obor
n20:CC
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
4
n3:pocetUcastnikuAkce
0
n3:pocetZahranicnichUcastnikuAkce
0
n3:projekt
n19:GA303%2F00%2FD062
n3:rokUplatneniVysledku
n18:2001
n3:tvurceVysledku
Slanina, Jiří Táborská, Eva Schram, Karl H. Miketová, Petra
n3:typAkce
n6:WRD
n3:zahajeniAkce
2001-01-01+01:00
s:numberOfPages
2
n16:hasPublisher
American Society for Mass Spectrometry
n14:organizacniJednotka
14110