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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F00%3A00003561%21RIV09-GA0-14110___
rdf:type
n7:Vysledek skos:Concept
dcterms:description
Extracts from artichoke (Cynara scolymus L.) or cardoon (Cynara cardunculus L., Asteraceae), are widely used in phytotherapy as choleretic, hypocholesterolemic and hepatoprotective agents (Kraft, 1997). The cholesterol-lowering effect of artichoke extracts was confirmed by numerous animal experiments and recently by a controlled clinical trial. The possible mechanism of hypocholesterolemic activity involves choleretic action, reduction of cholesterol biosynthesis and inhibition of low density lipoprotein oxidation (Pittler and Ernst, 1998). The antiatherosclerotic and antihepatotoxic activities can be mediated by antioxidative action of the artichoke extract. These activities have been ascribed to the phenolic compounds present in the extract. According to HPLC analysis, the methanol extract of C. cardunculus leaves contained three main phenolic components, 5-caffeoylquinic acid (chlorogenic acid), 1,5-dicaffeoylquinic acid (1,5-DiCQA) and flavonoid luteolin-7-O-glucoside. However, caffeoylquinic acid Extracts from artichoke (Cynara scolymus L.) or cardoon (Cynara cardunculus L., Asteraceae), are widely used in phytotherapy as choleretic, hypocholesterolemic and hepatoprotective agents (Kraft, 1997). The cholesterol-lowering effect of artichoke extracts was confirmed by numerous animal experiments and recently by a controlled clinical trial. The possible mechanism of hypocholesterolemic activity involves choleretic action, reduction of cholesterol biosynthesis and inhibition of low density lipoprotein oxidation (Pittler and Ernst, 1998). The antiatherosclerotic and antihepatotoxic activities can be mediated by antioxidative action of the artichoke extract. These activities have been ascribed to the phenolic compounds present in the extract. According to HPLC analysis, the methanol extract of C. cardunculus leaves contained three main phenolic components, 5-caffeoylquinic acid (chlorogenic acid), 1,5-dicaffeoylquinic acid (1,5-DiCQA) and flavonoid luteolin-7-O-glucoside. However, caffeoylquinic acid Extracts from artichoke (Cynara scolymus L.) or cardoon (Cynara cardunculus L., Asteraceae), are widely used in phytotherapy as choleretic, hypocholesterolemic and hepatoprotective agents (Kraft, 1997). The cholesterol-lowering effect of artichoke extracts was confirmed by numerous animal experiments and recently by a controlled clinical trial. The possible mechanism of hypocholesterolemic activity involves choleretic action, reduction of cholesterol biosynthesis and inhibition of low density lipoprotein oxidation (Pittler and Ernst, 1998). The antiatherosclerotic and antihepatotoxic activities can be mediated by antioxidative action of the artichoke extract. These activities have been ascribed to the phenolic compounds present in the extract. According to HPLC analysis, the methanol extract of C. cardunculus leaves contained three main phenolic components, 5-caffeoylquinic acid (chlorogenic acid), 1,5-dicaffeoylquinic acid (1,5-DiCQA) and flavonoid luteolin-7-O-glucoside. However, caffeoylquinic acid
dcterms:title
Antiradical phenolic compounds from Cynara cardunculus Antiradical phenolic compounds from Cynara cardunculus Antiradical phenolic compounds from Cynara cardunculus
skos:prefLabel
Antiradical phenolic compounds from Cynara cardunculus Antiradical phenolic compounds from Cynara cardunculus Antiradical phenolic compounds from Cynara cardunculus
skos:notation
RIV/00216224:14110/00:00003561!RIV09-GA0-14110___
n3:aktivita
n14:P
n3:aktivity
P(GA303/00/D062)
n3:dodaniDat
n5:2009
n3:domaciTvurceVysledku
n9:3682455 n9:9382925 n9:7045182 n9:2115549
n3:druhVysledku
n20:D
n3:duvernostUdaju
n8:S
n3:entitaPredkladatele
n10:predkladatel
n3:idSjednocenehoVysledku
704839
n3:idVysledku
RIV/00216224:14110/00:00003561
n3:jazykVysledku
n17:eng
n3:klicovaSlova
Antiradical; phenolics; Cynara cardunculus; DPPH
n3:klicoveSlovo
n15:Cynara%20cardunculus n15:DPPH n15:Antiradical n15:phenolics
n3:kontrolniKodProRIV
[F0C4985BAC91]
n3:mistoKonaniAkce
září 2000, Freising-Weihenstephan, BRD
n3:mistoVydani
Freising-Weihenstephan, BRD
n3:nazevZdroje
In Polyphenols Communication 2000. XX th International Conference on Polyphenols
n3:obor
n4:CE
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
4
n3:projekt
n18:GA303%2F00%2FD062
n3:rokUplatneniVysledku
n5:2000
n3:tvurceVysledku
Bochořáková, Hana Slanina, Jiří Paulová, Hana Táborská, Eva
n3:typAkce
n19:CST
n3:zahajeniAkce
2000-01-01+01:00
s:numberOfPages
2
n13:hasPublisher
S.Martens, D.Treutter, G.Forkmann, str.425
n16:organizacniJednotka
14110