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Statements

Subject Item
n2:RIV%2F00216208%3A11510%2F10%3A10071295%21RIV11-MSM-11510___
rdf:type
skos:Concept n12:Vysledek
dcterms:description
Creatine (CR), is recommended for application as food supplement. It is supposed that human organism uses it for formation of CR phosphate as source of energy. In our short-term experiments we have observed changes in the metabolism of two-carbon (2C) units and of thiolic substances 4 to 6 hours after CR supplementation. The level of thiodiglycolic acid (TDGA) in urine increased rapidly and then decreased again to the original level. The level of TDGA in urine is a marker of disturbance in metabolic pathways of 2C units and of thiolic compounds. Our long-term CR supplementation, revealed that the biochemical pathways, affected by CR application included intrinsic participation of vitamin B12 and folates. The levels of those two vitamins changed in a mutually reverse way. The men under study can be divided into 4 different groups according to changes of CR levels found in urine, and of levels of folates and vitamin B12, determined in blood before and after CR administration. Creatine (CR), is recommended for application as food supplement. It is supposed that human organism uses it for formation of CR phosphate as source of energy. In our short-term experiments we have observed changes in the metabolism of two-carbon (2C) units and of thiolic substances 4 to 6 hours after CR supplementation. The level of thiodiglycolic acid (TDGA) in urine increased rapidly and then decreased again to the original level. The level of TDGA in urine is a marker of disturbance in metabolic pathways of 2C units and of thiolic compounds. Our long-term CR supplementation, revealed that the biochemical pathways, affected by CR application included intrinsic participation of vitamin B12 and folates. The levels of those two vitamins changed in a mutually reverse way. The men under study can be divided into 4 different groups according to changes of CR levels found in urine, and of levels of folates and vitamin B12, determined in blood before and after CR administration.
dcterms:title
Effect of Creatine Applied as Food Supplement on Human Metabolism Effect of Creatine Applied as Food Supplement on Human Metabolism
skos:prefLabel
Effect of Creatine Applied as Food Supplement on Human Metabolism Effect of Creatine Applied as Food Supplement on Human Metabolism
skos:notation
RIV/00216208:11510/10:10071295!RIV11-MSM-11510___
n3:aktivita
n10:Z
n3:aktivity
Z(MSM0021620864)
n3:dodaniDat
n4:2011
n3:domaciTvurceVysledku
n11:9106278 n11:8399689
n3:druhVysledku
n15:O
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
255921
n3:idVysledku
RIV/00216208:11510/10:10071295
n3:jazykVysledku
n14:eng
n3:klicovaSlova
thiodiglycolic acid (TDGA); homocysteine; human metabolism; vitamin B12; folate; supplementation; creatine
n3:klicoveSlovo
n6:homocysteine n6:thiodiglycolic%20acid%20%28TDGA%29 n6:creatine n6:folate n6:vitamin%20B12 n6:human%20metabolism n6:supplementation
n3:kontrolniKodProRIV
[78DC68F9AEE1]
n3:obor
n5:FB
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
4
n3:rokUplatneniVysledku
n4:2010
n3:tvurceVysledku
Přistoupilová, Kamila Petr, Miroslav Kohlíková, Eva Navrátil, Tomáš
n3:zamer
n17:MSM0021620864
n13:organizacniJednotka
11510