This HTML5 document contains 41 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
n20http://linked.opendata.cz/ontology/domain/vavai/riv/typAkce/
dctermshttp://purl.org/dc/terms/
n11http://localhost/temp/predkladatel/
n9http://purl.org/net/nknouf/ns/bibtex#
n13http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n8http://linked.opendata.cz/ontology/domain/vavai/
n16https://schema.org/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n19http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00216208%3A11320%2F14%3A10290901%21RIV15-MSM-11320___/
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n5http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n7http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n17http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n14http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n18http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n15http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n4http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00216208%3A11320%2F14%3A10290901%21RIV15-MSM-11320___
rdf:type
skos:Concept n8:Vysledek
dcterms:description
Luminescence spectroscopy gains attention as a tool for medical diagnosis, since it can provide prompt diagnostic results at low cost with minimal or none at all invasiveness. Photosensitizers, fluorescent drugs for photodynamic therapy selectively uptaken in diseased tissues, enable identification and demarcation of lesions thanks to its intense emission, which is easy to detect. However, the attention turns towards employment of tissue autofluorescence to distinguish between healthy and diseased tissues. Autofluorescence requires no extrinsic drugs as it utilizes emission of naturally occurring cofactors. This offers another advantage, as the emission of cofactors reveals information about metabolic state of the cells. However, the autofluorescence of tissues is rather weak and emission of particular cofactors often overlaps. This requires employment of time-resolved detection, which offers excellent sensitivity and ability to distinguish emission from individual fluorophores based on their differing lifetimes. Moreover, the lifetimes may reflect binding state of the cofactors and thus provide more detailed information about their biologic functions. This paper reviews the main principles of luminescence diagnosis of tissues and introduces newly designed multichannel set-up for simultaneous time-resolved detection of emission up to four naturally occurring intrinsic fluorophores such as NADP, FAD, Protoporphyrin IX, and collagen or elastin which provide information about metabolic and morphological properties of diagnosed tissues. The very preliminary results obtained on fluorescence standards are presented. Luminescence spectroscopy gains attention as a tool for medical diagnosis, since it can provide prompt diagnostic results at low cost with minimal or none at all invasiveness. Photosensitizers, fluorescent drugs for photodynamic therapy selectively uptaken in diseased tissues, enable identification and demarcation of lesions thanks to its intense emission, which is easy to detect. However, the attention turns towards employment of tissue autofluorescence to distinguish between healthy and diseased tissues. Autofluorescence requires no extrinsic drugs as it utilizes emission of naturally occurring cofactors. This offers another advantage, as the emission of cofactors reveals information about metabolic state of the cells. However, the autofluorescence of tissues is rather weak and emission of particular cofactors often overlaps. This requires employment of time-resolved detection, which offers excellent sensitivity and ability to distinguish emission from individual fluorophores based on their differing lifetimes. Moreover, the lifetimes may reflect binding state of the cofactors and thus provide more detailed information about their biologic functions. This paper reviews the main principles of luminescence diagnosis of tissues and introduces newly designed multichannel set-up for simultaneous time-resolved detection of emission up to four naturally occurring intrinsic fluorophores such as NADP, FAD, Protoporphyrin IX, and collagen or elastin which provide information about metabolic and morphological properties of diagnosed tissues. The very preliminary results obtained on fluorescence standards are presented.
dcterms:title
Photodiagnostics and Luminescence Diagnostics of Cancer Photodiagnostics and Luminescence Diagnostics of Cancer
skos:prefLabel
Photodiagnostics and Luminescence Diagnostics of Cancer Photodiagnostics and Luminescence Diagnostics of Cancer
skos:notation
RIV/00216208:11320/14:10290901!RIV15-MSM-11320___
n3:aktivita
n14:I
n3:aktivity
I
n3:dodaniDat
n4:2015
n3:domaciTvurceVysledku
n13:1920855 n13:1133268
n3:druhVysledku
n18:D
n3:duvernostUdaju
n7:S
n3:entitaPredkladatele
n19:predkladatel
n3:idSjednocenehoVysledku
36480
n3:idVysledku
RIV/00216208:11320/14:10290901
n3:jazykVysledku
n17:eng
n3:klicovaSlova
TCSPC; fluorescence; time-resolved detection; Photodiagnosis
n3:klicoveSlovo
n5:time-resolved%20detection n5:Photodiagnosis n5:TCSPC n5:fluorescence
n3:kontrolniKodProRIV
[E56C5FA6513E]
n3:mistoKonaniAkce
Prague
n3:mistoVydani
Prague
n3:nazevZdroje
WDS 2014 - Proceedings of Contributed Papers - - Physics
n3:obor
n15:BO
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
2
n3:rokUplatneniVysledku
n4:2014
n3:tvurceVysledku
Dědic, Roman Stíbal, Adam
n3:typAkce
n20:WRD
n3:zahajeniAkce
2014-06-03+02:00
s:numberOfPages
8
n9:hasPublisher
Matfyzpress
n16:isbn
978-80-7378-276-4
n11:organizacniJednotka
11320