This HTML5 document contains 51 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n18http://localhost/temp/predkladatel/
n14http://purl.org/net/nknouf/ns/bibtex#
n12http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n17http://linked.opendata.cz/resource/domain/vavai/subjekt/
n16http://linked.opendata.cz/ontology/domain/vavai/
n15https://schema.org/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
rdfshttp://www.w3.org/2000/01/rdf-schema#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n20http://bibframe.org/vocab/
n4http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00216208%3A11310%2F13%3A10140214%21RIV14-MSM-11310___/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n8http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n10http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n22http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n13http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n21http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n19http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n7http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00216208%3A11310%2F13%3A10140214%21RIV14-MSM-11310___
rdf:type
skos:Concept n16:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.1002/9781118503652.ch3
dcterms:description
Fundamental requirements for MRI contrast agents (CAs) are high thermodynamic stability and kinetic inertness to assure low toxicity of the CAs, and at least one coordination site available for coordination of a water molecule which is crucial for the contrast enhancement. The clinically approved gadolinium (Gd)(III)-based CAs utilize octadentate ligands. This chapter is dedicated to the synthesis and characterization of ligands and their Gd(III) complexes. First, it talks about the CAs employing linear polyamine scaffold, and CAs employing cyclen scaffold. Next, the chapter presents representative examples of the polyaminopolycarboxylic bifunctional ligands and conjugation strategies utilized in the frame of MRI research. Description of the ligand syntheses is mostly presented in accordance with the ligand motif. Finally, the chapter describes synthesis and characterization of the lanthanide (Ln)(III) complexes. Fundamental requirements for MRI contrast agents (CAs) are high thermodynamic stability and kinetic inertness to assure low toxicity of the CAs, and at least one coordination site available for coordination of a water molecule which is crucial for the contrast enhancement. The clinically approved gadolinium (Gd)(III)-based CAs utilize octadentate ligands. This chapter is dedicated to the synthesis and characterization of ligands and their Gd(III) complexes. First, it talks about the CAs employing linear polyamine scaffold, and CAs employing cyclen scaffold. Next, the chapter presents representative examples of the polyaminopolycarboxylic bifunctional ligands and conjugation strategies utilized in the frame of MRI research. Description of the ligand syntheses is mostly presented in accordance with the ligand motif. Finally, the chapter describes synthesis and characterization of the lanthanide (Ln)(III) complexes.
dcterms:title
Synthesis and Characterization of Ligands and their Gadolinium(III) Complexes Synthesis and Characterization of Ligands and their Gadolinium(III) Complexes
skos:prefLabel
Synthesis and Characterization of Ligands and their Gadolinium(III) Complexes Synthesis and Characterization of Ligands and their Gadolinium(III) Complexes
skos:notation
RIV/00216208:11310/13:10140214!RIV14-MSM-11310___
n16:predkladatel
n17:orjk%3A11310
n3:aktivita
n13:I
n3:aktivity
I
n3:dodaniDat
n7:2014
n3:domaciTvurceVysledku
n12:3978877 n12:9417850 n12:3062228 n12:9695656
n3:druhVysledku
n21:C
n3:duvernostUdaju
n10:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
109471
n3:idVysledku
RIV/00216208:11310/13:10140214
n3:jazykVysledku
n22:eng
n3:klicovaSlova
MRI; linear polyamine scaffold; ligands; lanthanide (Ln) complexes; gadolinium (GD) C omplexes; cyclen scaffold; contrast agents; bifunctional ligands
n3:klicoveSlovo
n8:gadolinium%20%28GD%29%20C%20omplexes n8:MRI n8:contrast%20agents n8:cyclen%20scaffold n8:bifunctional%20ligands n8:linear%20polyamine%20scaffold n8:ligands n8:lanthanide%20%28Ln%29%20complexes
n3:kontrolniKodProRIV
[4425B9303BE4]
n3:mistoVydani
Chichester, West Sussex PO19 8SQ United Kingdom
n3:nazevEdiceCisloSvazku
neuveden
n3:nazevZdroje
The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging, Second Edition
n3:obor
n19:CA
n3:pocetDomacichTvurcuVysledku
4
n3:pocetStranKnihy
496
n3:pocetTvurcuVysledku
4
n3:rokUplatneniVysledku
n7:2013
n3:tvurceVysledku
Hermann, Petr Kotek, Jan Lukeš, Ivan Kubíček, Vojtěch
s:numberOfPages
73
n20:doi
10.1002/9781118503652.ch3
n14:hasPublisher
John Wiley & Sons, Ltd
n15:isbn
978-1-119-99176-2
n18:organizacniJednotka
11310