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Statements

Subject Item
n2:RIV%2F00216208%3A11310%2F12%3A10126733%21RIV13-GA0-11310___
rdf:type
skos:Concept n3:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.1016/j.proche.2012.10.130
dcterms:description
New voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite film in the role of a transducer was used for the investigation of the interaction between model carcinogenic substance (2-aminofluorene; one of the most extensively studied examples of the aromatic amine class of carcinogens) and calf thymus double-stranded DNA (dsDNA). The layer of dsDNA immobilized at the electrode surface was utilized as a biocomponent responsive interface. The biosensor was characterized regarding the detection of DNA damage (induced by direct interaction with 2-aminofluorene) using square wave voltammetric responses of the guanine and adenine moieties and cyclic voltammetric responses of the anionic redox indicator [Fe(CN)6]4-/3- present in the solution. New voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite film in the role of a transducer was used for the investigation of the interaction between model carcinogenic substance (2-aminofluorene; one of the most extensively studied examples of the aromatic amine class of carcinogens) and calf thymus double-stranded DNA (dsDNA). The layer of dsDNA immobilized at the electrode surface was utilized as a biocomponent responsive interface. The biosensor was characterized regarding the detection of DNA damage (induced by direct interaction with 2-aminofluorene) using square wave voltammetric responses of the guanine and adenine moieties and cyclic voltammetric responses of the anionic redox indicator [Fe(CN)6]4-/3- present in the solution.
dcterms:title
Voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite transducer Voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite transducer
skos:prefLabel
Voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite transducer Voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite transducer
skos:notation
RIV/00216208:11310/12:10126733!RIV13-GA0-11310___
n3:predkladatel
n4:orjk%3A11310
n5:aktivita
n13:Z n13:P n13:I
n5:aktivity
I, P(GBP206/12/G151), Z(MSM0021620857)
n5:cisloPeriodika
April
n5:dodaniDat
n11:2013
n5:domaciTvurceVysledku
n16:4454472 n16:8805865
n5:druhVysledku
n6:J
n5:duvernostUdaju
n9:S
n5:entitaPredkladatele
n19:predkladatel
n5:idSjednocenehoVysledku
178551
n5:idVysledku
RIV/00216208:11310/12:10126733
n5:jazykVysledku
n21:eng
n5:klicovaSlova
2-aminofluorene; carbon film electrode; voltammetry; DNA damage detection; electrochemical DNA biosensor
n5:klicoveSlovo
n7:2-aminofluorene n7:DNA%20damage%20detection n7:electrochemical%20DNA%20biosensor n7:carbon%20film%20electrode n7:voltammetry
n5:kodStatuVydavatele
NL - Nizozemsko
n5:kontrolniKodProRIV
[AC3207BAAD1B]
n5:nazevZdroje
Procedia Chemistry [online]
n5:obor
n12:CG
n5:pocetDomacichTvurcuVysledku
2
n5:pocetTvurcuVysledku
2
n5:projekt
n18:GBP206%2F12%2FG151
n5:rokUplatneniVysledku
n11:2012
n5:svazekPeriodika
6
n5:tvurceVysledku
Barek, Jiří Vyskočil, Vlastimil
n5:wos
000313216900008
n5:zamer
n8:MSM0021620857
s:issn
1876-6196
s:numberOfPages
8
n20:doi
10.1016/j.proche.2012.10.130
n14:organizacniJednotka
11310