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Statements

Subject Item
n2:RIV%2F00216208%3A11310%2F10%3A10081196%21RIV11-MSM-11310___
rdf:type
n12:Vysledek skos:Concept
dcterms:description
Antibody (IgG) responses to the saliva of Phlebotomus argentipes were investigated using serum samples from regions of India endemic and non-endemic for visceral leishmaniasis (VL). By pre-adsorbing the sera against the saliva of the competing human-biting but non-VL vector P.papatasi. we significantly improved the specificity of a P.argentipes saliva enzyme-linked immunosorbent assay. Using this method, we observed a statistically significant correlation between antibodies to P argenitpes saliva and the average indoor density of female sand flies. Additionally, the method was able to detect recent changes in vector exposure when sera from VL patients were assayed before, during, and after hospitalization and protected from sand fly bites under untreated bed nets. Collectively, these results highlight the utility of antibodies to P.argentipes saliva as an important tool to evaluate VL vector control programs. Antibody (IgG) responses to the saliva of Phlebotomus argentipes were investigated using serum samples from regions of India endemic and non-endemic for visceral leishmaniasis (VL). By pre-adsorbing the sera against the saliva of the competing human-biting but non-VL vector P.papatasi. we significantly improved the specificity of a P.argentipes saliva enzyme-linked immunosorbent assay. Using this method, we observed a statistically significant correlation between antibodies to P argenitpes saliva and the average indoor density of female sand flies. Additionally, the method was able to detect recent changes in vector exposure when sera from VL patients were assayed before, during, and after hospitalization and protected from sand fly bites under untreated bed nets. Collectively, these results highlight the utility of antibodies to P.argentipes saliva as an important tool to evaluate VL vector control programs.
dcterms:title
Measurement of Recent Exposure to Phlebotomus argentipes, the Vector of Indian Visceral Leishmaniasis, by Using Human Antibody Responses to Sand Fly Saliva Measurement of Recent Exposure to Phlebotomus argentipes, the Vector of Indian Visceral Leishmaniasis, by Using Human Antibody Responses to Sand Fly Saliva
skos:prefLabel
Measurement of Recent Exposure to Phlebotomus argentipes, the Vector of Indian Visceral Leishmaniasis, by Using Human Antibody Responses to Sand Fly Saliva Measurement of Recent Exposure to Phlebotomus argentipes, the Vector of Indian Visceral Leishmaniasis, by Using Human Antibody Responses to Sand Fly Saliva
skos:notation
RIV/00216208:11310/10:10081196!RIV11-MSM-11310___
n4:aktivita
n13:P n13:Z
n4:aktivity
P(LC06009), Z(MSM0021620828)
n4:cisloPeriodika
5
n4:dodaniDat
n6:2011
n4:domaciTvurceVysledku
n14:6447910 n14:2493063 n14:7188056
n4:druhVysledku
n9:J
n4:duvernostUdaju
n18:S
n4:entitaPredkladatele
n17:predkladatel
n4:idSjednocenehoVysledku
270033
n4:idVysledku
RIV/00216208:11310/10:10081196
n4:jazykVysledku
n7:eng
n4:klicovaSlova
MARKER; CHAGASI; GLAND ANTIGENS; IMMUNE-RESPONSE; LUTZOMYIA-LONGIPALPIS SALIVA
n4:klicoveSlovo
n5:CHAGASI n5:LUTZOMYIA-LONGIPALPIS%20SALIVA n5:MARKER n5:GLAND%20ANTIGENS n5:IMMUNE-RESPONSE
n4:kodStatuVydavatele
US - Spojené státy americké
n4:kontrolniKodProRIV
[AE7D383586F2]
n4:nazevZdroje
American Journal of Tropical Medicine and Hygiene
n4:obor
n19:EG
n4:pocetDomacichTvurcuVysledku
3
n4:pocetTvurcuVysledku
18
n4:projekt
n10:LC06009
n4:rokUplatneniVysledku
n6:2010
n4:svazekPeriodika
82
n4:tvurceVysledku
Das, Pradeep Hamilton, Gordno Sundar, Shyam Volf, Petr Müller, Ingrid Rogers, Matthew E. Rijal, Suman Dinesh, Diwakar Gidwani, Kamlesh Davies, Clive R. Volfová, Věra Kumar, Rajiv Clements, Meredith Das, Murari Boelaert, Marleen Picado, Albert Kumar, Vijay Hostomská, Jitka
n4:wos
000277406500010
n4:zamer
n11:MSM0021620828
s:issn
0002-9637
s:numberOfPages
7
n16:organizacniJednotka
11310