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Statements

Subject Item
n2:RIV%2F00216208%3A11310%2F09%3A10000084%21RIV10-GA0-11310___
rdf:type
skos:Concept n17:Vysledek
dcterms:description
Background: In rodents, the cell surface complement regulatory protein CD46 is expressed solely on the spermatozoal acrosome membrane. Ablation of the CD46 gene is associated with a faster acrosome reaction. Sperm from Apodemus flavicollis (yellow-necked field mice), A. microps (pygmy field mice) and A. sylvaticus (European wood mice) fail to express CD46 protein and exhibit a more rapid acrosome reaction rate than Mus (house mice) or BALB/c mice. A. agrarius (striped field mice) belong to a different Apodemus subgenus and have pronounced promiscuity and large relative testis size. The aim of this study was to determine whether A. agrarius sperm fail to express CD46 protein and, if so, whether A. agrarius have a faster acrosome reaction than Mus. Background: In rodents, the cell surface complement regulatory protein CD46 is expressed solely on the spermatozoal acrosome membrane. Ablation of the CD46 gene is associated with a faster acrosome reaction. Sperm from Apodemus flavicollis (yellow-necked field mice), A. microps (pygmy field mice) and A. sylvaticus (European wood mice) fail to express CD46 protein and exhibit a more rapid acrosome reaction rate than Mus (house mice) or BALB/c mice. A. agrarius (striped field mice) belong to a different Apodemus subgenus and have pronounced promiscuity and large relative testis size. The aim of this study was to determine whether A. agrarius sperm fail to express CD46 protein and, if so, whether A. agrarius have a faster acrosome reaction than Mus.
dcterms:title
Absence of spermatozoal CD46 protein expression and associated rapid acrosome reaction rate in striped field mice (Apodemus agrarius) Absence of spermatozoal CD46 protein expression and associated rapid acrosome reaction rate in striped field mice (Apodemus agrarius)
skos:prefLabel
Absence of spermatozoal CD46 protein expression and associated rapid acrosome reaction rate in striped field mice (Apodemus agrarius) Absence of spermatozoal CD46 protein expression and associated rapid acrosome reaction rate in striped field mice (Apodemus agrarius)
skos:notation
RIV/00216208:11310/09:10000084!RIV10-GA0-11310___
n3:aktivita
n9:P n9:Z
n3:aktivity
P(1M06011), P(GA206/07/0779), Z(AV0Z60930519), Z(MSM0021620828)
n3:cisloPeriodika
april 16
n3:dodaniDat
n15:2010
n3:domaciTvurceVysledku
n7:7214448 n7:8580855 n7:8996164 n7:6610676
n3:druhVysledku
n5:J
n3:duvernostUdaju
n13:S
n3:entitaPredkladatele
n10:predkladatel
n3:idSjednocenehoVysledku
301713
n3:idVysledku
RIV/00216208:11310/09:10000084
n3:jazykVysledku
n19:eng
n3:klicovaSlova
Membrane cofactor protein; messenger-rna degradation; testicular germ-cells; preferential expression; molecular cloning; genus apodemus; sperm; mouse; mcp; genes
n3:klicoveSlovo
n4:genes n4:sperm n4:Membrane%20cofactor%20protein n4:mouse n4:genus%20apodemus n4:messenger-rna%20degradation n4:preferential%20expression n4:molecular%20cloning n4:testicular%20germ-cells n4:mcp
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[FB61D5E3E64F]
n3:nazevZdroje
Reproductive Biology and Endocrinology
n3:obor
n6:EG
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
8
n3:projekt
n12:GA206%2F07%2F0779 n12:1M06011
n3:rokUplatneniVysledku
n15:2009
n3:svazekPeriodika
7
n3:tvurceVysledku
Hortová, Kateřina Flanagan, Brian F Stopka, Pavel Andrlíková, Petra Johnson, Peter M. Bryja, Josef Frolíková, Michaela Clift, Leanne E
n3:wos
000266491100001
n3:zamer
n14:MSM0021620828 n14:AV0Z60930519
s:issn
1477-7827
s:numberOfPages
9
n18:organizacniJednotka
11310