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Statements

Subject Item
n2:RIV%2F00216208%3A11160%2F11%3A10100602%21RIV12-GA0-11160___
rdf:type
n11:Vysledek skos:Concept
rdfs:seeAlso
http://www.sciencedirect.com/science/article/pii/S0021967310016249
dcterms:description
Hydrophilic interaction liquid chromatography (HILIC) was used to analyze dexrazoxane and its three metabolites on different stationary phases. Initial experiments were done with HPLC-UV and subsequently LC-MS were used to confirm applicability of the selected conditions. In addition, LC-MS behavior of all analytes were studied and characterized. Hydrophilic interaction liquid chromatography (HILIC) was used to analyze dexrazoxane and its three metabolites on different stationary phases. Initial experiments were done with HPLC-UV and subsequently LC-MS were used to confirm applicability of the selected conditions. In addition, LC-MS behavior of all analytes were studied and characterized.
dcterms:title
Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites - The cardioprotectant dexrazoxane as a model case Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites - The cardioprotectant dexrazoxane as a model case
skos:prefLabel
Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites - The cardioprotectant dexrazoxane as a model case Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites - The cardioprotectant dexrazoxane as a model case
skos:notation
RIV/00216208:11160/11:10100602!RIV12-GA0-11160___
n11:predkladatel
n19:orjk%3A11160
n4:aktivita
n5:P n5:Z
n4:aktivity
P(GPP206/10/P439), Z(MSM0021620822)
n4:cisloPeriodika
3
n4:dodaniDat
n8:2012
n4:domaciTvurceVysledku
n9:3923223 n9:3787362 n9:6128688 n9:9864202 n9:3249719
n4:druhVysledku
n21:J
n4:duvernostUdaju
n13:S
n4:entitaPredkladatele
n17:predkladatel
n4:idSjednocenehoVysledku
203154
n4:idVysledku
RIV/00216208:11160/11:10100602
n4:jazykVysledku
n16:eng
n4:klicovaSlova
LC-MS; Polar drug; Bisdioxopiperazine; Dexrazoxane; Hydrophilic interaction liquid chromatography
n4:klicoveSlovo
n7:Dexrazoxane n7:LC-MS n7:Bisdioxopiperazine n7:Hydrophilic%20interaction%20liquid%20chromatography n7:Polar%20drug
n4:kodStatuVydavatele
NL - Nizozemsko
n4:kontrolniKodProRIV
[1CB530440F0E]
n4:nazevZdroje
Journal of Chromatography A
n4:obor
n22:FR
n4:pocetDomacichTvurcuVysledku
5
n4:pocetTvurcuVysledku
5
n4:projekt
n18:GPP206%2F10%2FP439
n4:rokUplatneniVysledku
n8:2011
n4:svazekPeriodika
1218
n4:tvurceVysledku
Hrušková, Kateřina Kovaříková, Petra Klimeš, Jiří Stariat, Ján Vávrová, Kateřina
n4:wos
000286680900008
n4:zamer
n10:MSM0021620822
s:issn
0021-9673
s:numberOfPages
11
n15:doi
10.1016/j.chroma.2010.11.050
n20:organizacniJednotka
11160