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Statements

Subject Item
n2:RIV%2F00216208%3A11160%2F11%3A10100446%21RIV12-MSM-11160___
rdf:type
n7:Vysledek skos:Concept
rdfs:seeAlso
http://www.sciencedirect.com/science/article/pii/S0162013411000316
dcterms:description
26 flavonoids were analyzed for their iron chelating activity and stability of the formed complexes in four patho/physiologically relevant pH conditions (4.5, 5.5, 6.8, 7.5) and compared with clinically used iron chelator deferoxamine. The study demonstrated that the most effective iron binding site of flavonoids represented 6,7-dihydroxy structure present in baicalein which was not inferior in all tested pH to deferoxamine. 26 flavonoids were analyzed for their iron chelating activity and stability of the formed complexes in four patho/physiologically relevant pH conditions (4.5, 5.5, 6.8, 7.5) and compared with clinically used iron chelator deferoxamine. The study demonstrated that the most effective iron binding site of flavonoids represented 6,7-dihydroxy structure present in baicalein which was not inferior in all tested pH to deferoxamine.
dcterms:title
In vitro analysis of iron chelating activity of flavonoids In vitro analysis of iron chelating activity of flavonoids
skos:prefLabel
In vitro analysis of iron chelating activity of flavonoids In vitro analysis of iron chelating activity of flavonoids
skos:notation
RIV/00216208:11160/11:10100446!RIV12-MSM-11160___
n7:predkladatel
n8:orjk%3A11160
n3:aktivita
n20:S
n3:aktivity
S
n3:cisloPeriodika
5
n3:dodaniDat
n12:2012
n3:domaciTvurceVysledku
n4:2446197 n4:4608496 n4:9905952 n4:8859183 n4:1600664 n4:2389991
n3:druhVysledku
n19:J
n3:duvernostUdaju
n11:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
204027
n3:idVysledku
RIV/00216208:11160/11:10100446
n3:jazykVysledku
n16:eng
n3:klicovaSlova
Deferoxamine; Antioxidants; Ferrozine; Chelation; Iron; Flavonoids
n3:klicoveSlovo
n5:Ferrozine n5:Chelation n5:Antioxidants n5:Flavonoids n5:Deferoxamine n5:Iron
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[EF17069C539F]
n3:nazevZdroje
Journal of Inorganic Biochemistry
n3:obor
n18:FR
n3:pocetDomacichTvurcuVysledku
6
n3:pocetTvurcuVysledku
9
n3:rokUplatneniVysledku
n12:2011
n3:svazekPeriodika
105
n3:tvurceVysledku
Hrdina, Radomír Jahodář, Luděk Proietti Silvestri, Ilaria Filipský, Tomáš Mladěnka, Přemysl Bovicelli, Paolo Saso, Luciano Zatloukalová, Libuše Macáková, Kateřina
n3:wos
000290923100014
s:issn
0162-0134
s:numberOfPages
9
n10:doi
10.1016/j.jinorgbio.2011.02.003
n13:organizacniJednotka
11160