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Statements

Subject Item
n2:RIV%2F00216208%3A11150%2F13%3A10135333%21RIV14-MSM-11150___
rdf:type
skos:Concept n8:Vysledek
dcterms:description
The association of hostility and insight ratings (PANSS items) with medication adherence measured by Hayward scale was investigated in 443 first episode patients diagnosed with schizophrenia, schizoaffective disorder or schizophreniform disorder. The patients took part in the EUFEST study. Prospectively, high hostility score at baseline significantly predicted nonadherence at 1st month of treatment and low insight at baseline significantly predicted nonadherence at months 1, 6 and 12. The increase of hostility and decrease in insight (over 4 points in PANSS ratings) resulted in an additive OR (95% cofidence limits) for both variables of 73, 5 at month 1, OR 276,1 at month 3 and OR 77,6 at month 6. Lack of insight and its decrease appear to have greater and more stable predictive association with adherence than hostility. The effects of both variables on adherence do not interact. The association of hostility and insight ratings (PANSS items) with medication adherence measured by Hayward scale was investigated in 443 first episode patients diagnosed with schizophrenia, schizoaffective disorder or schizophreniform disorder. The patients took part in the EUFEST study. Prospectively, high hostility score at baseline significantly predicted nonadherence at 1st month of treatment and low insight at baseline significantly predicted nonadherence at months 1, 6 and 12. The increase of hostility and decrease in insight (over 4 points in PANSS ratings) resulted in an additive OR (95% cofidence limits) for both variables of 73, 5 at month 1, OR 276,1 at month 3 and OR 77,6 at month 6. Lack of insight and its decrease appear to have greater and more stable predictive association with adherence than hostility. The effects of both variables on adherence do not interact.
dcterms:title
Insight and Hostility as Predictors and Correlates of Nonadherence in the European First Episode Schizophrenia Trial Insight and Hostility as Predictors and Correlates of Nonadherence in the European First Episode Schizophrenia Trial
skos:prefLabel
Insight and Hostility as Predictors and Correlates of Nonadherence in the European First Episode Schizophrenia Trial Insight and Hostility as Predictors and Correlates of Nonadherence in the European First Episode Schizophrenia Trial
skos:notation
RIV/00216208:11150/13:10135333!RIV14-MSM-11150___
n8:predkladatel
n9:orjk%3A11150
n4:aktivita
n15:N
n4:aktivity
N
n4:cisloPeriodika
2
n4:dodaniDat
n11:2014
n4:domaciTvurceVysledku
n10:2617536
n4:druhVysledku
n13:J
n4:duvernostUdaju
n12:S
n4:entitaPredkladatele
n18:predkladatel
n4:idSjednocenehoVysledku
80404
n4:idVysledku
RIV/00216208:11150/13:10135333
n4:jazykVysledku
n17:eng
n4:klicovaSlova
disorder; medication; 1st episode schizophrenia; Antipsychotic-drugs
n4:klicoveSlovo
n14:medication n14:1st%20episode%20schizophrenia n14:Antipsychotic-drugs n14:disorder
n4:kodStatuVydavatele
US - Spojené státy americké
n4:kontrolniKodProRIV
[AEC13FE6896D]
n4:nazevZdroje
Journal of Clinical Psychopharmacology
n4:obor
n16:FL
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
7
n4:rokUplatneniVysledku
n11:2013
n4:svazekPeriodika
33
n4:tvurceVysledku
Czobor, Pál Kahn, Rene S. Libiger, Jan Fleischhacker, W. Wolfgang Volavka, Jan Bitter, István Derks, Eske M.
n4:wos
000316303700023
s:issn
0271-0749
s:numberOfPages
4
n6:organizacniJednotka
11150