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Statements

Subject Item
n2:RIV%2F00216208%3A11150%2F09%3A00208653%21RIV10-MO0-11150___
rdf:type
n10:Vysledek skos:Concept
dcterms:description
Hematopoietic stem cell (HSC) is one of the most radiosensitive cells in organism. In mice it is characterized as lin-Sca-1+CD117+ cell. This review discusses role of HSC subpopulations in recovery of hematopoiesis after irradiation, and molecular mechanisms of reaction of HSC to damage induced by genotoxic stress, mainly to double strand breaks of DNA. Hematopoietic stem cell (HSC) is one of the most radiosensitive cells in organism. In mice it is characterized as lin-Sca-1+CD117+ cell. This review discusses role of HSC subpopulations in recovery of hematopoiesis after irradiation, and molecular mechanisms of reaction of HSC to damage induced by genotoxic stress, mainly to double strand breaks of DNA.
dcterms:title
Apoptosis and Senescence - Main Mechanisms of Accelerated Aging of Haematopoietic Cells after Irradiation Apoptosis and Senescence - Main Mechanisms of Accelerated Aging of Haematopoietic Cells after Irradiation
skos:prefLabel
Apoptosis and Senescence - Main Mechanisms of Accelerated Aging of Haematopoietic Cells after Irradiation Apoptosis and Senescence - Main Mechanisms of Accelerated Aging of Haematopoietic Cells after Irradiation
skos:notation
RIV/00216208:11150/09:00208653!RIV10-MO0-11150___
n3:aktivita
n13:Z n13:P
n3:aktivity
P(GA304/08/0329), Z(MO0FVZ0000501)
n3:cisloPeriodika
2
n3:dodaniDat
n7:2010
n3:domaciTvurceVysledku
n17:6518672
n3:druhVysledku
n18:J
n3:duvernostUdaju
n11:S
n3:entitaPredkladatele
n12:predkladatel
n3:idSjednocenehoVysledku
303717
n3:idVysledku
RIV/00216208:11150/09:00208653
n3:jazykVysledku
n19:eng
n3:klicovaSlova
haematopoietic stem cell; radiation; apoptosis; senescence
n3:klicoveSlovo
n5:haematopoietic%20stem%20cell n5:senescence n5:apoptosis n5:radiation
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[244951E93923]
n3:nazevZdroje
Acta Veterinaria Brno
n3:obor
n9:CE
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
2
n3:projekt
n16:GA304%2F08%2F0329
n3:rokUplatneniVysledku
n7:2009
n3:svazekPeriodika
78
n3:tvurceVysledku
Řezáčová, Martina Vávrová, Jiřina
n3:wos
000267788000003
n3:zamer
n4:MO0FVZ0000501
s:issn
0001-7213
s:numberOfPages
13
n14:organizacniJednotka
11150