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Statements

Subject Item
n2:RIV%2F00216208%3A11140%2F14%3A10271585%21RIV15-MSM-11140___
rdf:type
n14:Vysledek skos:Concept
dcterms:description
Mycosis fungoides (MF) displays a broad spectrum of clinical, histological, and phenotypic variants with different prognostic impact. CD8(+)CD56(+) MF is very rare. So far, only 5 patients with CD8(+)CD56(+) MF were reported to date. All of the previously described patients with this phenotypic variant were adults at the time of diagnosis and often manifested with widespread poikilodermatous skin lesions. Here we describe the clinicopathological features of a juvenile form of CD8(+)CD56(+) non-poikilodermatous MF in a 10-year-old girl. In our patient, the disease displayed an indolent course and excellent prognosis with complete remission after treatment with UV light, topical steroids, and methotrexate. The differential diagnosis of CD8(+) epidermotropic lymphocytic infiltrates in children is discussed, and the cases of CD8(+)CD56(+) MF reported in the literature are reviewed. Mycosis fungoides (MF) displays a broad spectrum of clinical, histological, and phenotypic variants with different prognostic impact. CD8(+)CD56(+) MF is very rare. So far, only 5 patients with CD8(+)CD56(+) MF were reported to date. All of the previously described patients with this phenotypic variant were adults at the time of diagnosis and often manifested with widespread poikilodermatous skin lesions. Here we describe the clinicopathological features of a juvenile form of CD8(+)CD56(+) non-poikilodermatous MF in a 10-year-old girl. In our patient, the disease displayed an indolent course and excellent prognosis with complete remission after treatment with UV light, topical steroids, and methotrexate. The differential diagnosis of CD8(+) epidermotropic lymphocytic infiltrates in children is discussed, and the cases of CD8(+)CD56(+) MF reported in the literature are reviewed.
dcterms:title
Pediatric CD8(+)CD56(+) Non-poikilodermatous Mycosis Fungoides: Case Report and Review of the Literature Pediatric CD8(+)CD56(+) Non-poikilodermatous Mycosis Fungoides: Case Report and Review of the Literature
skos:prefLabel
Pediatric CD8(+)CD56(+) Non-poikilodermatous Mycosis Fungoides: Case Report and Review of the Literature Pediatric CD8(+)CD56(+) Non-poikilodermatous Mycosis Fungoides: Case Report and Review of the Literature
skos:notation
RIV/00216208:11140/14:10271585!RIV15-MSM-11140___
n4:aktivita
n5:I
n4:aktivity
I
n4:cisloPeriodika
7
n4:dodaniDat
n17:2015
n4:domaciTvurceVysledku
n7:5892805
n4:druhVysledku
n8:J
n4:duvernostUdaju
n11:S
n4:entitaPredkladatele
n15:predkladatel
n4:idSjednocenehoVysledku
36040
n4:idVysledku
RIV/00216208:11140/14:10271585
n4:jazykVysledku
n16:eng
n4:klicovaSlova
child; pediatric; juvenile; natural killer; CD56; cytotoxic lymphoma; mycosis fungoides; cutaneous lymphoma
n4:klicoveSlovo
n6:pediatric n6:CD56 n6:child n6:cytotoxic%20lymphoma n6:cutaneous%20lymphoma n6:juvenile n6:natural%20killer n6:mycosis%20fungoides
n4:kodStatuVydavatele
US - Spojené státy americké
n4:kontrolniKodProRIV
[AA181AA24EB4]
n4:nazevZdroje
American Journal of Dermatopathology
n4:obor
n10:FP
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
4
n4:rokUplatneniVysledku
n17:2014
n4:svazekPeriodika
36
n4:tvurceVysledku
Metze, Dieter Kazakov, Dmitry Broekaert, Sigrid M. C. Kempf, Werner
n4:wos
000338531700014
s:issn
0193-1091
s:numberOfPages
5
n12:organizacniJednotka
11140