This HTML5 document contains 51 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n17http://localhost/temp/predkladatel/
n6http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n3http://linked.opendata.cz/ontology/domain/vavai/
n5http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00216208%3A11140%2F14%3A10218694%21RIV15-MSM-11140___/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
rdfshttp://www.w3.org/2000/01/rdf-schema#
n4http://linked.opendata.cz/ontology/domain/vavai/riv/
n14http://bibframe.org/vocab/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n10http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n8http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n18http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n13http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n19http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n15http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n9http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00216208%3A11140%2F14%3A10218694%21RIV15-MSM-11140___
rdf:type
n3:Vysledek skos:Concept
rdfs:seeAlso
http://link.springer.com/article/10.1007%2Fs00330-014-3223-9
dcterms:description
To investigate the potential contribution of iodine uptake calculation from dual-phase dual-energy CT (DE-CT) for lymph node staging and therapy response monitoring in lung cancer patients. Retrospective analysis of 27 patients with non-small cell lung carcinoma (NSCLC), who underwent dual-phase DE-CT before and after chemotherapy, was performed. Iodine uptake (mg/mL) and total iodine uptake (mg) were calculated using prototype software in the early (arterial) and late (venous) post-contrast circulatory phase in 110 mediastinal lymph nodes. The arterial enhancement fraction (AEF) was calculated and compared with lymph node size and response to chemotherapy. A significant difference of AEF was observed between enlarged (90.4 %; 32.3-238.5 %) and non-enlarged (72.7 %; -37.5-237.5 %) lymph nodes (p = 0.044) before treatment onset. A significantly different change of AEF in responding (decrease of 26.3 %; p = 0.022) and non-responding (increase of 43.0 %; p = 0.031) lymph nodes was demonstrated. A higher value of AEF before treatment was observed in lymph nodes with subsequent favourable response (88.6 % vs. 77.7 %; p = 0.122), but this difference did not reach statistical significance. The dual-phase DE-CT examination with quantification of ratio of early and late post-contrast iodine uptake is a feasible and promising method for the functional evaluation of mediastinal lymph nodes including therapy response assessment. To investigate the potential contribution of iodine uptake calculation from dual-phase dual-energy CT (DE-CT) for lymph node staging and therapy response monitoring in lung cancer patients. Retrospective analysis of 27 patients with non-small cell lung carcinoma (NSCLC), who underwent dual-phase DE-CT before and after chemotherapy, was performed. Iodine uptake (mg/mL) and total iodine uptake (mg) were calculated using prototype software in the early (arterial) and late (venous) post-contrast circulatory phase in 110 mediastinal lymph nodes. The arterial enhancement fraction (AEF) was calculated and compared with lymph node size and response to chemotherapy. A significant difference of AEF was observed between enlarged (90.4 %; 32.3-238.5 %) and non-enlarged (72.7 %; -37.5-237.5 %) lymph nodes (p = 0.044) before treatment onset. A significantly different change of AEF in responding (decrease of 26.3 %; p = 0.022) and non-responding (increase of 43.0 %; p = 0.031) lymph nodes was demonstrated. A higher value of AEF before treatment was observed in lymph nodes with subsequent favourable response (88.6 % vs. 77.7 %; p = 0.122), but this difference did not reach statistical significance. The dual-phase DE-CT examination with quantification of ratio of early and late post-contrast iodine uptake is a feasible and promising method for the functional evaluation of mediastinal lymph nodes including therapy response assessment.
dcterms:title
Dual-phase dual-energy CT in patients with lung cancer: assessment of the additional value of iodine quantification in lymph node therapy response Dual-phase dual-energy CT in patients with lung cancer: assessment of the additional value of iodine quantification in lymph node therapy response
skos:prefLabel
Dual-phase dual-energy CT in patients with lung cancer: assessment of the additional value of iodine quantification in lymph node therapy response Dual-phase dual-energy CT in patients with lung cancer: assessment of the additional value of iodine quantification in lymph node therapy response
skos:notation
RIV/00216208:11140/14:10218694!RIV15-MSM-11140___
n4:aktivita
n13:I
n4:aktivity
I
n4:cisloPeriodika
8
n4:dodaniDat
n9:2015
n4:domaciTvurceVysledku
n6:2185571 n6:7611390 n6:5563828 n6:1771361
n4:druhVysledku
n15:J
n4:duvernostUdaju
n8:S
n4:entitaPredkladatele
n5:predkladatel
n4:idSjednocenehoVysledku
12477
n4:idVysledku
RIV/00216208:11140/14:10218694
n4:jazykVysledku
n18:eng
n4:klicovaSlova
Therapy response; Lymph nodes; Lung cancer; Iodine contrast medium; Dual-energy CT
n4:klicoveSlovo
n10:Lymph%20nodes n10:Iodine%20contrast%20medium n10:Dual-energy%20CT n10:Lung%20cancer n10:Therapy%20response
n4:kodStatuVydavatele
DE - Spolková republika Německo
n4:kontrolniKodProRIV
[194EF8DB0700]
n4:nazevZdroje
European Radiology
n4:obor
n19:FP
n4:pocetDomacichTvurcuVysledku
4
n4:pocetTvurcuVysledku
8
n4:rokUplatneniVysledku
n9:2014
n4:svazekPeriodika
24
n4:tvurceVysledku
Schmidt, Bernhard Růžičková Kirchnerová, Olga Matoušková, Táňa Baxa, Jan Ferda, Jiří Sedlmair, Martin Vondráková, Alena Flohr, Thomas
n4:wos
000339271800032
s:issn
0938-7994
s:numberOfPages
8
n14:doi
10.1007/s00330-014-3223-9
n17:organizacniJednotka
11140