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Statements

Subject Item
n2:RIV%2F00216208%3A11140%2F14%3A10210627%21RIV15-MSM-11140___
rdf:type
n6:Vysledek skos:Concept
dcterms:description
The occurrence of basal cell carcinoma (BCC) of the vulva i rare. We report the case of a 79-year-old woman with a medical history of intravaginal condyloma acuminatum and vaginal intraepithelial neoplasia 3 (VaIN 3) who presented with a solitary whitish lesion sized 8x5 mm with a central desquamation located on the right labium majus. Histopathologic examination revealed a typical superficial and nodular BCC. Additionally, there were multiple remarkable foci of epidermolytic hyperkeratosis (EH). These foci both merged with superficial BCC or were sharply demarcated from the tumor. Retrospective molecular-biological examination of all the available materiál revealed HPV type 42 in both condyloma acuminatum and VaIN 3 specimen but not in the BCC associated with EH. To our best knowledge, involvement of the lower female genitalia by EH i a rare finding with six cases published to date. Awareness of EH in this location and its distinction is important because it may be potentially misinterpreted as a viral condyloma. The occurrence of basal cell carcinoma (BCC) of the vulva i rare. We report the case of a 79-year-old woman with a medical history of intravaginal condyloma acuminatum and vaginal intraepithelial neoplasia 3 (VaIN 3) who presented with a solitary whitish lesion sized 8x5 mm with a central desquamation located on the right labium majus. Histopathologic examination revealed a typical superficial and nodular BCC. Additionally, there were multiple remarkable foci of epidermolytic hyperkeratosis (EH). These foci both merged with superficial BCC or were sharply demarcated from the tumor. Retrospective molecular-biological examination of all the available materiál revealed HPV type 42 in both condyloma acuminatum and VaIN 3 specimen but not in the BCC associated with EH. To our best knowledge, involvement of the lower female genitalia by EH i a rare finding with six cases published to date. Awareness of EH in this location and its distinction is important because it may be potentially misinterpreted as a viral condyloma.
dcterms:title
Epidermolytic hyperkeratosis of the vulva associated with basal cell carcinoma in a patient with vaginal condyloma acuminatum and vaginal intraepithelial neoplasia harboring HPV, type 42 Epidermolytic hyperkeratosis of the vulva associated with basal cell carcinoma in a patient with vaginal condyloma acuminatum and vaginal intraepithelial neoplasia harboring HPV, type 42
skos:prefLabel
Epidermolytic hyperkeratosis of the vulva associated with basal cell carcinoma in a patient with vaginal condyloma acuminatum and vaginal intraepithelial neoplasia harboring HPV, type 42 Epidermolytic hyperkeratosis of the vulva associated with basal cell carcinoma in a patient with vaginal condyloma acuminatum and vaginal intraepithelial neoplasia harboring HPV, type 42
skos:notation
RIV/00216208:11140/14:10210627!RIV15-MSM-11140___
n3:aktivita
n10:I
n3:aktivity
I
n3:cisloPeriodika
2
n3:dodaniDat
n16:2015
n3:domaciTvurceVysledku
n4:7629990 n4:5892805 n4:1719793 n4:6058884
n3:druhVysledku
n11:J
n3:duvernostUdaju
n17:S
n3:entitaPredkladatele
n15:predkladatel
n3:idSjednocenehoVysledku
14851
n3:idVysledku
RIV/00216208:11140/14:10210627
n3:jazykVysledku
n12:eng
n3:klicovaSlova
human papillomavirus; epidermolytic hyperkeratosis; basal cell carcinoma; vulva
n3:klicoveSlovo
n9:epidermolytic%20hyperkeratosis n9:basal%20cell%20carcinoma n9:human%20papillomavirus n9:vulva
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[4FE656EDF3A2]
n3:nazevZdroje
Česko-slovenská patologie a Soudní lékařství
n3:obor
n13:FP
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
4
n3:rokUplatneniVysledku
n16:2014
n3:svazekPeriodika
50
n3:tvurceVysledku
Kazakov, Dmitry Kašpírková, Jana Kacerovská, Denisa Michal, Michal
s:issn
1210-7875
s:numberOfPages
3
n14:organizacniJednotka
11140