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Statements

Subject Item
n2:RIV%2F00216208%3A11140%2F13%3A10139623%21RIV14-MSM-11140___
rdf:type
n13:Vysledek skos:Concept
dcterms:description
Cribriform adenocarcinoma of the tongue and minor salivary glands (CATMSG) is a tumor occurring mostly, but not exclusively, in the base of the tongue. Other locations are minor salivary glands of the oral cavity. Histopathologically, CATMSG resembles papillary carcinoma of the thyroid gland. It usually reveals a solid growth devoid of colloid, and eosinophilic material present in follicular areas is rather pale in contrast to metastatic foci seen in papillary thyroid carcinoma that shows typical deeply eosinophilic colloid with %22moth-eaten peripheries%22 and cystic configuration. In addition, giant multinucleated cells are not observed in CATMSG and psammoma bodies are found only exceptionally. Unlike papillary thyroid carcinoma, CATMSG is composed of hybrid secretory-myoepithelial cells. Most importantly, CATMSG is consistently negative with both thyroglobulin and TTF-1. CATMSG is a distinct tumor entity that also differs from polymorphous low-grade adenocarcinoma by location, cytology, histological architecture, and behavior, with frequent metastases at the time of presentation. Paradoxically, early metastatic disease seen in most cases of CATMSG is associated with an indolent behavior. It makes CATMSG a unique neoplasm among all low-grade salivary gland tumors. Cribriform adenocarcinoma of the tongue and minor salivary glands (CATMSG) is a tumor occurring mostly, but not exclusively, in the base of the tongue. Other locations are minor salivary glands of the oral cavity. Histopathologically, CATMSG resembles papillary carcinoma of the thyroid gland. It usually reveals a solid growth devoid of colloid, and eosinophilic material present in follicular areas is rather pale in contrast to metastatic foci seen in papillary thyroid carcinoma that shows typical deeply eosinophilic colloid with %22moth-eaten peripheries%22 and cystic configuration. In addition, giant multinucleated cells are not observed in CATMSG and psammoma bodies are found only exceptionally. Unlike papillary thyroid carcinoma, CATMSG is composed of hybrid secretory-myoepithelial cells. Most importantly, CATMSG is consistently negative with both thyroglobulin and TTF-1. CATMSG is a distinct tumor entity that also differs from polymorphous low-grade adenocarcinoma by location, cytology, histological architecture, and behavior, with frequent metastases at the time of presentation. Paradoxically, early metastatic disease seen in most cases of CATMSG is associated with an indolent behavior. It makes CATMSG a unique neoplasm among all low-grade salivary gland tumors.
dcterms:title
Cribriform adenocarcinoma of the tongue and minor salivary glands: a review Cribriform adenocarcinoma of the tongue and minor salivary glands: a review
skos:prefLabel
Cribriform adenocarcinoma of the tongue and minor salivary glands: a review Cribriform adenocarcinoma of the tongue and minor salivary glands: a review
skos:notation
RIV/00216208:11140/13:10139623!RIV14-MSM-11140___
n13:predkladatel
n14:orjk%3A11140
n3:aktivita
n6:I
n3:aktivity
I
n3:cisloPeriodika
Suppl. 1
n3:dodaniDat
n17:2014
n3:domaciTvurceVysledku
n11:7629990 n11:5892805 n11:6058884
n3:druhVysledku
n9:J
n3:duvernostUdaju
n19:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
67292
n3:idVysledku
RIV/00216208:11140/13:10139623
n3:jazykVysledku
n12:eng
n3:klicovaSlova
hybrid secretory and myoepithelial cells; myosecretory cells; polymorphous low-grade adenocarcinoma; tongue; cribriform adenocarcinoma of minor salivay glands
n3:klicoveSlovo
n8:hybrid%20secretory%20and%20myoepithelial%20cells n8:polymorphous%20low-grade%20adenocarcinoma n8:tongue n8:cribriform%20adenocarcinoma%20of%20minor%20salivay%20glands n8:myosecretory%20cells
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[C7BC03412006]
n3:nazevZdroje
Head and Neck Pathology
n3:obor
n15:FP
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
3
n3:rokUplatneniVysledku
n17:2013
n3:svazekPeriodika
7
n3:tvurceVysledku
Kacerovská, Denisa Michal, Michal Kazakov, Dmitry
s:issn
1936-055X
s:numberOfPages
9
n7:doi
10.1007/s12105-013-0457-9
n18:organizacniJednotka
11140