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Statements

Subject Item
n2:RIV%2F00216208%3A11140%2F11%3A10105783%21RIV12-MZ0-11140___
rdf:type
n3:Vysledek skos:Concept
rdfs:seeAlso
http://www.sciencedirect.com/science/article/pii/S1092913410000778
dcterms:description
A 34-year-old pregnant woman with bilateral kidney tumors 9.5 and 2.5 cm in maximum diameter is presented. The larger tumor was clear renal cell carcinoma. The smaller contralateral tumor was focally HMB45 positive and had unusual histomorphology, including features resembling clear renal cell carcinoma with features of both t(6;11)- and t(X;17)/ASPL-TFE3 carcinomas. This tumor displayed a complex karyotype. A novel germ line mutation in the VHL gene (c.439A}G/p.I147V) was also identified in this patient A 34-year-old pregnant woman with bilateral kidney tumors 9.5 and 2.5 cm in maximum diameter is presented. The larger tumor was clear renal cell carcinoma. The smaller contralateral tumor was focally HMB45 positive and had unusual histomorphology, including features resembling clear renal cell carcinoma with features of both t(6;11)- and t(X;17)/ASPL-TFE3 carcinomas. This tumor displayed a complex karyotype. A novel germ line mutation in the VHL gene (c.439A}G/p.I147V) was also identified in this patient
dcterms:title
Bilateral renal tumors; conventional clear cell carcinoma and contralateral t(6;11)/t(X;17)-like tumor Histomorphologic, immunohistochemical, ultrastructural and molecular genetic studies including the report of a novel mutation in the VHL gene Bilateral renal tumors; conventional clear cell carcinoma and contralateral t(6;11)/t(X;17)-like tumor Histomorphologic, immunohistochemical, ultrastructural and molecular genetic studies including the report of a novel mutation in the VHL gene
skos:prefLabel
Bilateral renal tumors; conventional clear cell carcinoma and contralateral t(6;11)/t(X;17)-like tumor Histomorphologic, immunohistochemical, ultrastructural and molecular genetic studies including the report of a novel mutation in the VHL gene Bilateral renal tumors; conventional clear cell carcinoma and contralateral t(6;11)/t(X;17)-like tumor Histomorphologic, immunohistochemical, ultrastructural and molecular genetic studies including the report of a novel mutation in the VHL gene
skos:notation
RIV/00216208:11140/11:10105783!RIV12-MZ0-11140___
n3:predkladatel
n15:orjk%3A11140
n5:aktivita
n20:P
n5:aktivity
P(NS9722)
n5:cisloPeriodika
5
n5:dodaniDat
n13:2012
n5:domaciTvurceVysledku
n6:3182975 n6:7211139 n6:7629990 n6:9342710
n5:druhVysledku
n18:J
n5:duvernostUdaju
n16:S
n5:entitaPredkladatele
n19:predkladatel
n5:idSjednocenehoVysledku
188200
n5:idVysledku
RIV/00216208:11140/11:10105783
n5:jazykVysledku
n11:eng
n5:klicovaSlova
VHL gene germ line mutation; Comparative genomic hybridization; HMB45; Translocation associated renal tumor; Clear cell renal cell carcinoma; Kidney
n5:klicoveSlovo
n10:Comparative%20genomic%20hybridization n10:HMB45 n10:Kidney n10:Translocation%20associated%20renal%20tumor n10:Clear%20cell%20renal%20cell%20carcinoma n10:VHL%20gene%20germ%20line%20mutation
n5:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n5:kontrolniKodProRIV
[E0C0C0A8BCF7]
n5:nazevZdroje
Annals of Diagnostic Pathology
n5:obor
n17:FP
n5:pocetDomacichTvurcuVysledku
4
n5:pocetTvurcuVysledku
7
n5:projekt
n9:NS9722
n5:rokUplatneniVysledku
n13:2011
n5:svazekPeriodika
15
n5:tvurceVysledku
Halbhuber, Zbyněk Vaněček, Tomáš Hora, Milan Petersson, Fredrik Trivunic, Sandra Michal, Michal Hes, Ondřej
n5:wos
000295347200012
s:issn
1092-9134
s:numberOfPages
8
n21:doi
10.1016/j.anndiagpath.2010.05.004
n12:organizacniJednotka
11140