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Statements

Subject Item
n2:RIV%2F00216208%3A11130%2F14%3A10292858%21RIV15-MSM-11130___
rdf:type
n9:Vysledek skos:Concept
rdfs:seeAlso
http://dx.doi.org/10.3174/ajnr.A3996
dcterms:description
BACKGROUND AND PURPOSE: MRA is widely accepted as a noninvasive diagnostic tool for the detection of intracranial aneurysms, but detection is still a challenging task with rather low detection rates. Our aim was to examine the performance of a computer-aided diagnosis algorithm for detecting intracranial aneurysms on MRA in a clinical setting. MATERIALS AND METHODS: Aneurysm detectability was evaluated retrospectively in 48 subjects with and without computer-aided diagnosis by 6 readers using a clinical 3D viewing system. Aneurysms ranged from 1.1 to 6.0 mm (mean = 3.12 mm, median = 2.50 mm). We conducted a multireader, multicase, double-crossover design, free-response, observer-performance study on sets of images from different MRA scanners by using DSA as the reference standard. Jackknife alternative free-response operating characteristic curve analysis with the figure of merit was used. RESULTS: For all readers combined, the mean figure of merit improved from 0.655 to 0.759, indicating a change in the figure of merit attributable to computer-aided diagnosis of 0.10 (95% Cl, 0.03-0.18), which was statistically significant (F-1,F-47 = 7.00, P = .011). Five of the 6 radiologists had improved performance with computer-aided diagnosis, primarily due to increased sensitivity. CONCLUSIONS: In conditions similar to clinical practice, using computer-aided diagnosis significantly improved radiologists' detection of intracraniat DSA-confirmed aneurysms of {= 6 mm. BACKGROUND AND PURPOSE: MRA is widely accepted as a noninvasive diagnostic tool for the detection of intracranial aneurysms, but detection is still a challenging task with rather low detection rates. Our aim was to examine the performance of a computer-aided diagnosis algorithm for detecting intracranial aneurysms on MRA in a clinical setting. MATERIALS AND METHODS: Aneurysm detectability was evaluated retrospectively in 48 subjects with and without computer-aided diagnosis by 6 readers using a clinical 3D viewing system. Aneurysms ranged from 1.1 to 6.0 mm (mean = 3.12 mm, median = 2.50 mm). We conducted a multireader, multicase, double-crossover design, free-response, observer-performance study on sets of images from different MRA scanners by using DSA as the reference standard. Jackknife alternative free-response operating characteristic curve analysis with the figure of merit was used. RESULTS: For all readers combined, the mean figure of merit improved from 0.655 to 0.759, indicating a change in the figure of merit attributable to computer-aided diagnosis of 0.10 (95% Cl, 0.03-0.18), which was statistically significant (F-1,F-47 = 7.00, P = .011). Five of the 6 radiologists had improved performance with computer-aided diagnosis, primarily due to increased sensitivity. CONCLUSIONS: In conditions similar to clinical practice, using computer-aided diagnosis significantly improved radiologists' detection of intracraniat DSA-confirmed aneurysms of {= 6 mm.
dcterms:title
Computer-Aided Diagnosis Improves Detection of Small Intracranial Aneurysms on MRA in a Clinical Setting Computer-Aided Diagnosis Improves Detection of Small Intracranial Aneurysms on MRA in a Clinical Setting
skos:prefLabel
Computer-Aided Diagnosis Improves Detection of Small Intracranial Aneurysms on MRA in a Clinical Setting Computer-Aided Diagnosis Improves Detection of Small Intracranial Aneurysms on MRA in a Clinical Setting
skos:notation
RIV/00216208:11130/14:10292858!RIV15-MSM-11130___
n4:aktivita
n8:I n8:P
n4:aktivity
I, P(ED1.100/02/0123)
n4:cisloPeriodika
10
n4:dodaniDat
n10:2015
n4:domaciTvurceVysledku
n12:7562829
n4:druhVysledku
n6:J
n4:duvernostUdaju
n14:S
n4:entitaPredkladatele
n13:predkladatel
n4:idSjednocenehoVysledku
8506
n4:idVysledku
RIV/00216208:11130/14:10292858
n4:jazykVysledku
n20:eng
n4:klicovaSlova
single; observer; validation; prevalence; performance; images; accuracy; natural-history; multiple aneurysms; magnetic-resonance angiography
n4:klicoveSlovo
n5:prevalence n5:multiple%20aneurysms n5:performance n5:single n5:validation n5:observer n5:magnetic-resonance%20angiography n5:natural-history n5:images n5:accuracy
n4:kodStatuVydavatele
US - Spojené státy americké
n4:kontrolniKodProRIV
[27F7CF75A565]
n4:nazevZdroje
American Journal of Neuroradiology
n4:obor
n19:FH
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
15
n4:projekt
n16:ED1.100%2F02%2F0123
n4:rokUplatneniVysledku
n10:2014
n4:svazekPeriodika
35
n4:tvurceVysledku
Hejcl, A. Štěpán-Buksakowska, Irena Huston, J. Roček, Miloslav Diehn, F. E. Luetmer, P. H. Kaufmann, T. J. Yang, X. Erickson, B. J. Wood, C. P. Carter, R. Blezek, D. J. Horinek, D. Accurso, J. M. Hagen, C.
n4:wos
000342885700010
s:issn
0195-6108
s:numberOfPages
6
n18:doi
10.3174/ajnr.A3996
n17:organizacniJednotka
11130