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Statements

Subject Item
n2:RIV%2F00216208%3A11130%2F14%3A10292775%21RIV15-MSM-11130___
rdf:type
skos:Concept n13:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.1097/IGC.0000000000000062
dcterms:description
Objectives This study aimed to provide timely and effective guidance for pregnant women and health care providers to optimize maternal treatment and fetal protection and to promote effective management of the mother, fetus, and neonate when administering potentially teratogenic medications. New insights and more experience were gained since the first consensus meeting 5 years ago. Methods Members of the European Society of Gynecological Oncology task force Cancer in Pregnancy in concert with other international experts reviewed the existing literature on their respective areas of expertise. The summaries were subsequently merged into a complete article that served as a basis for discussion during the consensus meeting. All participants approved the final article. Results In the experts' view, cancer can be successfully treated during pregnancy in collaboration with a multidisciplinary team, optimizing maternal treatment while considering fetal safety. To maximize the maternal outcome, cancer treatment should follow a standard treatment protocol as for nonpregnant patients. Iatrogenic prematurity should be avoided. Individualization of treatment and effective psychologic support is imperative to provide throughout the pregnancy period. Diagnostic procedures, including staging examinations and imaging, such as magnetic resonance imaging and sonography, are preferable. Pelvic surgery, either open or laparoscopic, as part of a treatment protocol, may reveal beneficial outcomes and is preferably performed by experts. Most standard regimens of chemotherapy can be administered from 14 weeks gestational age onward. Apart from cervical and vulvar cancer, as well as important vulvar scarring, the mode of delivery is determined by the obstetrician. Objectives This study aimed to provide timely and effective guidance for pregnant women and health care providers to optimize maternal treatment and fetal protection and to promote effective management of the mother, fetus, and neonate when administering potentially teratogenic medications. New insights and more experience were gained since the first consensus meeting 5 years ago. Methods Members of the European Society of Gynecological Oncology task force Cancer in Pregnancy in concert with other international experts reviewed the existing literature on their respective areas of expertise. The summaries were subsequently merged into a complete article that served as a basis for discussion during the consensus meeting. All participants approved the final article. Results In the experts' view, cancer can be successfully treated during pregnancy in collaboration with a multidisciplinary team, optimizing maternal treatment while considering fetal safety. To maximize the maternal outcome, cancer treatment should follow a standard treatment protocol as for nonpregnant patients. Iatrogenic prematurity should be avoided. Individualization of treatment and effective psychologic support is imperative to provide throughout the pregnancy period. Diagnostic procedures, including staging examinations and imaging, such as magnetic resonance imaging and sonography, are preferable. Pelvic surgery, either open or laparoscopic, as part of a treatment protocol, may reveal beneficial outcomes and is preferably performed by experts. Most standard regimens of chemotherapy can be administered from 14 weeks gestational age onward. Apart from cervical and vulvar cancer, as well as important vulvar scarring, the mode of delivery is determined by the obstetrician.
dcterms:title
Gynecologic Cancers in Pregnancy Guidelines of a Second International Consensus Meeting Gynecologic Cancers in Pregnancy Guidelines of a Second International Consensus Meeting
skos:prefLabel
Gynecologic Cancers in Pregnancy Guidelines of a Second International Consensus Meeting Gynecologic Cancers in Pregnancy Guidelines of a Second International Consensus Meeting
skos:notation
RIV/00216208:11130/14:10292775!RIV15-MSM-11130___
n3:aktivita
n7:I
n3:aktivity
I
n3:cisloPeriodika
3
n3:dodaniDat
n15:2015
n3:domaciTvurceVysledku
n14:4745531
n3:druhVysledku
n8:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n9:predkladatel
n3:idSjednocenehoVysledku
18691
n3:idVysledku
RIV/00216208:11130/14:10292775
n3:jazykVysledku
n12:eng
n3:klicovaSlova
Gynecologic; Consensus; Chemotherapy; Pregnancy; Cancer
n3:klicoveSlovo
n11:Cancer n11:Pregnancy n11:Consensus n11:Gynecologic n11:Chemotherapy
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[66113EAA569A]
n3:nazevZdroje
International Journal of Gynecological Cancer
n3:obor
n5:FD
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
22
n3:rokUplatneniVysledku
n15:2014
n3:svazekPeriodika
24
n3:tvurceVysledku
Han, Sileny N. Lok, Christianne Ottevanger, Petronella B. Fumagalli, Monica Kesic, Vesna Lishner, Michael Amant, Frederic Fruscio, Robert Dekrem, Jana Berveiller, Paul Steffensen, Karina Dahl Nulman, Irena Morice, Philippe Halaška, Michael Uzan, Catherine Van Calsteren, Kristel van den Heuvel, Frank Strauven, Goedele Vergote, Ignace Mhallem Gziri, Mina Maxwell, Cynthia Mir, Olivier
n3:wos
000332519000005
s:issn
1048-891X
s:numberOfPages
10
n19:doi
10.1097/IGC.0000000000000062
n10:organizacniJednotka
11130