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Statements

Subject Item
n2:RIV%2F00216208%3A11130%2F14%3A10292757%21RIV15-MSM-11130___
rdf:type
skos:Concept n18:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.1016/j.ejogrb.2013.12.021
dcterms:description
Objectives: To monitor fetal anemia during administration of chemotherapy to the fetus's mother. Study design: Between 2007 and 2012 six patients with malignancy diagnosed during pregnancy were included in our prospective study. For evaluation of fetal anemia, peak systolic velocimetry (PSV) of the middle cerebral artery is considered the best method. The patients were repeatedly examined one day before and on the third day after the administration of chemotherapy. At least three measurements were performed and the highest value was used as appropriate. Multiples of the median (MoM) were calculated using the website http://www.perinatology.com/calculators/MCA.htm. When the MoM reached 1.29, moderate anemia was diagnosed. Results: The women's average age was 30 years. The average gestational age at diagnosis was 20.7 weeks of pregnancy. Borderline fetal anemia was detected in only in one patient. After delivery newborns were examined by standard pediatric evaluation and blood count was provided. There was no evidence of any newborn anemia. Conclusions: Chemotherapy administered during pregnancy is becoming more frequent due to increasing knowledge and data on such cases. Close monitoring of the fetus should be performed in specialized. centers. For detection of chemotherapy-induced anemia, PSV measurement should be employed. Objectives: To monitor fetal anemia during administration of chemotherapy to the fetus's mother. Study design: Between 2007 and 2012 six patients with malignancy diagnosed during pregnancy were included in our prospective study. For evaluation of fetal anemia, peak systolic velocimetry (PSV) of the middle cerebral artery is considered the best method. The patients were repeatedly examined one day before and on the third day after the administration of chemotherapy. At least three measurements were performed and the highest value was used as appropriate. Multiples of the median (MoM) were calculated using the website http://www.perinatology.com/calculators/MCA.htm. When the MoM reached 1.29, moderate anemia was diagnosed. Results: The women's average age was 30 years. The average gestational age at diagnosis was 20.7 weeks of pregnancy. Borderline fetal anemia was detected in only in one patient. After delivery newborns were examined by standard pediatric evaluation and blood count was provided. There was no evidence of any newborn anemia. Conclusions: Chemotherapy administered during pregnancy is becoming more frequent due to increasing knowledge and data on such cases. Close monitoring of the fetus should be performed in specialized. centers. For detection of chemotherapy-induced anemia, PSV measurement should be employed.
dcterms:title
A pilot study on peak systolic velocity monitoring of fetal anemia after administration of chemotherapy during pregnancy A pilot study on peak systolic velocity monitoring of fetal anemia after administration of chemotherapy during pregnancy
skos:prefLabel
A pilot study on peak systolic velocity monitoring of fetal anemia after administration of chemotherapy during pregnancy A pilot study on peak systolic velocity monitoring of fetal anemia after administration of chemotherapy during pregnancy
skos:notation
RIV/00216208:11130/14:10292757!RIV15-MSM-11130___
n3:aktivita
n15:I
n3:aktivity
I
n3:cisloPeriodika
neuveden
n3:dodaniDat
n7:2015
n3:domaciTvurceVysledku
n9:4745531 n9:9930795 n9:1850660 n9:7462395 n9:7298471
n3:druhVysledku
n17:J
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
1037
n3:idVysledku
RIV/00216208:11130/14:10292757
n3:jazykVysledku
n11:eng
n3:klicovaSlova
Anemia; PSV; Treatment; Pregnancy; Chemotherapy
n3:klicoveSlovo
n6:Pregnancy n6:Anemia n6:Treatment n6:PSV n6:Chemotherapy
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[46F826E163CD]
n3:nazevZdroje
European Journal of Obstetrics, Gynecology and Reproductive Biology
n3:obor
n14:FK
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
7
n3:rokUplatneniVysledku
n7:2014
n3:svazekPeriodika
174
n3:tvurceVysledku
Robová, Helena Halaška, Michael Vlk, Radovan Komár, Matej Rob, Lukáš Tomek, Viktor Skultety, J.
n3:wos
000333505500013
s:issn
0301-2115
s:numberOfPages
4
n10:doi
10.1016/j.ejogrb.2013.12.021
n13:organizacniJednotka
11130