This HTML5 document contains 44 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n19http://localhost/temp/predkladatel/
n6http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n11http://linked.opendata.cz/resource/domain/vavai/subjekt/
n10http://linked.opendata.cz/ontology/domain/vavai/
n14http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00216208%3A11130%2F13%3A10209759%21RIV14-MSM-11130___/
shttp://schema.org/
n4http://linked.opendata.cz/ontology/domain/vavai/riv/
rdfshttp://www.w3.org/2000/01/rdf-schema#
skoshttp://www.w3.org/2004/02/skos/core#
n18http://bibframe.org/vocab/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n7http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n16http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n8http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n5http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n20http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n9http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n17http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00216208%3A11130%2F13%3A10209759%21RIV14-MSM-11130___
rdf:type
skos:Concept n10:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.1007/s12185-013-1289-9
dcterms:description
Lymphoblasts of acute lymphoblastic leukemia origin reappeared in a male patient 34 years after the initial diagnosis. Comparison of DNA profiles of the initial and reappeared lymphoblasts revealed a partially identical sequence, indicating the possibility that these lymphoblasts may have been present as preleukemic stem cells at the time of diagnosis and remained dormant for a long period until additional events conferred proliferative activity to these dormant preleukemic stem cells. Thus, in some cases of very late relapse, the reappearance of lymphoblasts may not be due to the relapse of the original leukemic clone, but to a clonal progression of a pre-existing subclone derived from preleukemic stem cells. Lymphoblasts of acute lymphoblastic leukemia origin reappeared in a male patient 34 years after the initial diagnosis. Comparison of DNA profiles of the initial and reappeared lymphoblasts revealed a partially identical sequence, indicating the possibility that these lymphoblasts may have been present as preleukemic stem cells at the time of diagnosis and remained dormant for a long period until additional events conferred proliferative activity to these dormant preleukemic stem cells. Thus, in some cases of very late relapse, the reappearance of lymphoblasts may not be due to the relapse of the original leukemic clone, but to a clonal progression of a pre-existing subclone derived from preleukemic stem cells.
dcterms:title
Reappearance of acute lymphoblastic leukemia 34 years after initial diagnosis: a case report and study of the origin of the reappeared blasts Reappearance of acute lymphoblastic leukemia 34 years after initial diagnosis: a case report and study of the origin of the reappeared blasts
skos:prefLabel
Reappearance of acute lymphoblastic leukemia 34 years after initial diagnosis: a case report and study of the origin of the reappeared blasts Reappearance of acute lymphoblastic leukemia 34 years after initial diagnosis: a case report and study of the origin of the reappeared blasts
skos:notation
RIV/00216208:11130/13:10209759!RIV14-MSM-11130___
n10:predkladatel
n11:orjk%3A11130
n4:aktivita
n5:I
n4:aktivity
I
n4:cisloPeriodika
4
n4:dodaniDat
n17:2014
n4:domaciTvurceVysledku
n6:3952851 n6:7396104
n4:druhVysledku
n20:J
n4:duvernostUdaju
n16:S
n4:entitaPredkladatele
n14:predkladatel
n4:idSjednocenehoVysledku
101659
n4:idVysledku
RIV/00216208:11130/13:10209759
n4:jazykVysledku
n8:eng
n4:klicovaSlova
Preleukemic stem cells; Late relapse; Acute lymphoblastic leukemia
n4:klicoveSlovo
n7:Acute%20lymphoblastic%20leukemia n7:Preleukemic%20stem%20cells n7:Late%20relapse
n4:kodStatuVydavatele
JP - Japonsko
n4:kontrolniKodProRIV
[84447B9EF8B8]
n4:nazevZdroje
International Journal of Hematology
n4:obor
n9:FD
n4:pocetDomacichTvurcuVysledku
2
n4:pocetTvurcuVysledku
4
n4:rokUplatneniVysledku
n17:2013
n4:svazekPeriodika
97
n4:tvurceVysledku
Takayama, Nobuyuki Bessho, Fumio Froňková, Eva Zuna, Jan
n4:wos
000317475500014
s:issn
0925-5710
s:numberOfPages
4
n18:doi
10.1007/s12185-013-1289-9
n19:organizacniJednotka
11130