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Statements

Subject Item
n2:RIV%2F00216208%3A11130%2F09%3A5354%21RIV10-MZ0-11130___
rdf:type
skos:Concept n16:Vysledek
dcterms:description
Background: Focal cortical dysplasia (FCD) is recognized as the major cause of focal intractable epilepsy in childhood. Various factors influencing postsurgical seizure outcome in pediatric patients with FCD have been reported. Objective: To analyze different variables in relation to seizure outcome in order to identify prognostic factors for selection of pediatric patients with FCD for epilepsy surgery. Methods: A cohort of 149 patients with histologically confirmed mild malformations of cortical development or FCD with at least 2 years of postoperative follow-up was retrospectively studied; 113 subjects had at least 5 years of postoperative follow-up. Twenty-eight clinical, EEG, MRI, neuropsychological, surgical, and histopathologic parameters were evaluated. Results: The only significant predictor of surgical success was completeness of surgical resection, defined as complete removal of the structural MRI lesion (if present) and the cortical region exhibiting prominent ictal and interictal abnormal Background: Focal cortical dysplasia (FCD) is recognized as the major cause of focal intractable epilepsy in childhood. Various factors influencing postsurgical seizure outcome in pediatric patients with FCD have been reported. Objective: To analyze different variables in relation to seizure outcome in order to identify prognostic factors for selection of pediatric patients with FCD for epilepsy surgery. Methods: A cohort of 149 patients with histologically confirmed mild malformations of cortical development or FCD with at least 2 years of postoperative follow-up was retrospectively studied; 113 subjects had at least 5 years of postoperative follow-up. Twenty-eight clinical, EEG, MRI, neuropsychological, surgical, and histopathologic parameters were evaluated. Results: The only significant predictor of surgical success was completeness of surgical resection, defined as complete removal of the structural MRI lesion (if present) and the cortical region exhibiting prominent ictal and interictal abnormal
dcterms:title
Incomplete resection of focal cortical dysplasia is the main predictor of poor postsurgical outcome Incomplete resection of focal cortical dysplasia is the main predictor of poor postsurgical outcome
skos:prefLabel
Incomplete resection of focal cortical dysplasia is the main predictor of poor postsurgical outcome Incomplete resection of focal cortical dysplasia is the main predictor of poor postsurgical outcome
skos:notation
RIV/00216208:11130/09:5354!RIV10-MZ0-11130___
n3:aktivita
n12:Z n12:P
n3:aktivity
P(NR8843), Z(MZ0FNM2005)
n3:cisloPeriodika
3
n3:dodaniDat
n7:2010
n3:domaciTvurceVysledku
n10:9525300
n3:druhVysledku
n15:J
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
318961
n3:idVysledku
RIV/00216208:11130/09:5354
n3:jazykVysledku
n14:eng
n3:klicovaSlova
pediatric epilepsy surgery; surgical-treatment; intractable epilepsy; intrinsic epileptogenicity; children; malformations; lesions; eeg; classification; subtypes
n3:klicoveSlovo
n8:intractable%20epilepsy n8:intrinsic%20epileptogenicity n8:classification n8:children n8:lesions n8:subtypes n8:eeg n8:pediatric%20epilepsy%20surgery n8:malformations n8:surgical-treatment
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[EDCDA7E01E2E]
n3:nazevZdroje
Neurology
n3:obor
n9:FH
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
13
n3:projekt
n4:NR8843
n3:rokUplatneniVysledku
n7:2009
n3:svazekPeriodika
72
n3:tvurceVysledku
Korman, B. Morrison, G. Dean, P. Duchowny, M. Pacheco-Jacome, E. Dunoyer, C. Resnick, T. Jayakar, P. Vinters, HV Ragheb, J. Rey, G. Kršek, Pavel Maton, B.
n3:wos
000262624300005
n3:zamer
n19:MZ0FNM2005
s:issn
0028-3878
s:numberOfPages
7
n18:organizacniJednotka
11130