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Statements

Subject Item
n2:RIV%2F00216208%3A11120%2F15%3A43909390%21RIV15-MSM-11120___
rdf:type
n14:Vysledek skos:Concept
dcterms:description
Background: Acute rhinosinusitis (ARS) has been shown to significantly reduce patient quality of life (QoL). While the QoL in patients with chronic rhinosinusitis has been the subject of intensive research over the last decade, studies measuring the impact of ARS on patient QoL have remained relatively scarce. The aim of this study was to determine the relationship between the QoL and parameters suggestive of acute bacterial rhinosinusitis (C-reactive protein [CRP] levels and positive culture) and to see if measurement of the QoL could be used as an indicator for antibiotic treatment in ARS. Methods: Eighty patients with ARS were enrolled in the study. A novel QoL instrument for patients with ARS, called Measurement of Acute Rhinosinusitis (MARS) questionnaire, was given to patients at the time of diagnosis. We assessed patient QoL, obtained endoscopically guided cultures from the middle meatus, and measured levels of CRP. The relationship between QoL MARS scores (QoL-Mscores) and CRP was determined using a correlation coefficient. To compare QoL-Mscores, relative to culture-positive and culture-negative patients, the Student's t-test was used. Results: No correlation between the QoL, assessed using the MARS questionnaire, and positive middle meatus culture was demonstrated (P = 0.332). A weak correlation was found between QoL-Mscores and CRP values, with a correlation coefficient of 0.221 and P = 0.0498. Conclusion: No correlation between the QoL in ARS patients and positive culture was found in this study. The clinical significance of the correlation between QoL-Mscores and CRP values in the antibiotic decision making process needs further research. Background: Acute rhinosinusitis (ARS) has been shown to significantly reduce patient quality of life (QoL). While the QoL in patients with chronic rhinosinusitis has been the subject of intensive research over the last decade, studies measuring the impact of ARS on patient QoL have remained relatively scarce. The aim of this study was to determine the relationship between the QoL and parameters suggestive of acute bacterial rhinosinusitis (C-reactive protein [CRP] levels and positive culture) and to see if measurement of the QoL could be used as an indicator for antibiotic treatment in ARS. Methods: Eighty patients with ARS were enrolled in the study. A novel QoL instrument for patients with ARS, called Measurement of Acute Rhinosinusitis (MARS) questionnaire, was given to patients at the time of diagnosis. We assessed patient QoL, obtained endoscopically guided cultures from the middle meatus, and measured levels of CRP. The relationship between QoL MARS scores (QoL-Mscores) and CRP was determined using a correlation coefficient. To compare QoL-Mscores, relative to culture-positive and culture-negative patients, the Student's t-test was used. Results: No correlation between the QoL, assessed using the MARS questionnaire, and positive middle meatus culture was demonstrated (P = 0.332). A weak correlation was found between QoL-Mscores and CRP values, with a correlation coefficient of 0.221 and P = 0.0498. Conclusion: No correlation between the QoL in ARS patients and positive culture was found in this study. The clinical significance of the correlation between QoL-Mscores and CRP values in the antibiotic decision making process needs further research.
dcterms:title
The relationship of C-reactive protein levels and positive culture with quality of life in acute rhinosinusitis The relationship of C-reactive protein levels and positive culture with quality of life in acute rhinosinusitis
skos:prefLabel
The relationship of C-reactive protein levels and positive culture with quality of life in acute rhinosinusitis The relationship of C-reactive protein levels and positive culture with quality of life in acute rhinosinusitis
skos:notation
RIV/00216208:11120/15:43909390!RIV15-MSM-11120___
n3:aktivita
n11:I
n3:aktivity
I
n3:cisloPeriodika
January 27
n3:dodaniDat
n13:2015
n3:domaciTvurceVysledku
n5:4892585 n5:8989907 n5:9531467
n3:druhVysledku
n12:J
n3:duvernostUdaju
n15:S
n3:entitaPredkladatele
n9:predkladatel
n3:idSjednocenehoVysledku
392
n3:idVysledku
RIV/00216208:11120/15:43909390
n3:jazykVysledku
n18:eng
n3:klicovaSlova
anti-bacterial agents; questionnaires; quality of life; endoscopy
n3:klicoveSlovo
n4:quality%20of%20life n4:anti-bacterial%20agents n4:questionnaires n4:endoscopy
n3:kodStatuVydavatele
NZ - Nový Zéland
n3:kontrolniKodProRIV
[EC1B730F12EA]
n3:nazevZdroje
Patient Preference and Adherence
n3:obor
n17:FF
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
3
n3:rokUplatneniVysledku
n13:2015
n3:svazekPeriodika
9
n3:tvurceVysledku
Schalek, Petr Hornáčková, Zuzana Hahn, Aleš
n3:wos
000348433400002
s:issn
1177-889X
s:numberOfPages
5
n10:doi
10.2147/PPA.S76915
n16:organizacniJednotka
11120