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Statements

Subject Item
n2:RIV%2F00216208%3A11120%2F14%3A43908256%21RIV15-MSM-11120___
rdf:type
skos:Concept n13:Vysledek
dcterms:description
Background: The incidence and treatment strategies of acute coronary syndrome (ACS) vary by region. Additionally, the clinical spectrum of ACS is changing and outcomes are improving. Aim: We assessed the incidence, treatment strategies, and outcomes of ACS for a well-defined population within a well-established network of percutaneous coronary intervention (PCI) centers and non-PCI centers. Methods: The CZECH-2 registry included 1221 consecutive patients (mean age: 68 ± 13 years; 63.4% males) admitted for suspected ACS to 32 hospitals (including 4 PCI centers) within four Czech counties (total population: 2,370,841 inhabitants) during a 2-month period. Results: The estimated incidence of confirmed ACS was 2149 cases/million/year. In 374 (31%) patients, ACS was ruled out during the hospital stay. Coronary angiography (CAG) was performed in 60% of the patients overall and PCI was performed in 59% of the confirmed ACS patients. Killip classifications II-IV on admission were more common in patients with final diagnosis of non ST-elevation myocardial infarction (NSTEMI) than ST-elevation myocardial infarction (STEMI) (37.1% vs. 22.8%; p < 0.001). The 30-day mortality rate was 5.7% for the whole study group, 7.3% for STEMI patients, 8.4% for NSTEMI patients, and 1.6% for patients with unstable angina pectoris (UAP), respectively. Conclusions: Almost one-third of the patients admitted for suspected ACS had a different final diagnosis. Among those with confirmed ACS, the use of CAG, PCI, CABG, and effective medications is rational. Outcome in NSTEMI patients was equivalent to those in STEMI patients, mainly due to the high-risk population in this group. Background: The incidence and treatment strategies of acute coronary syndrome (ACS) vary by region. Additionally, the clinical spectrum of ACS is changing and outcomes are improving. Aim: We assessed the incidence, treatment strategies, and outcomes of ACS for a well-defined population within a well-established network of percutaneous coronary intervention (PCI) centers and non-PCI centers. Methods: The CZECH-2 registry included 1221 consecutive patients (mean age: 68 ± 13 years; 63.4% males) admitted for suspected ACS to 32 hospitals (including 4 PCI centers) within four Czech counties (total population: 2,370,841 inhabitants) during a 2-month period. Results: The estimated incidence of confirmed ACS was 2149 cases/million/year. In 374 (31%) patients, ACS was ruled out during the hospital stay. Coronary angiography (CAG) was performed in 60% of the patients overall and PCI was performed in 59% of the confirmed ACS patients. Killip classifications II-IV on admission were more common in patients with final diagnosis of non ST-elevation myocardial infarction (NSTEMI) than ST-elevation myocardial infarction (STEMI) (37.1% vs. 22.8%; p < 0.001). The 30-day mortality rate was 5.7% for the whole study group, 7.3% for STEMI patients, 8.4% for NSTEMI patients, and 1.6% for patients with unstable angina pectoris (UAP), respectively. Conclusions: Almost one-third of the patients admitted for suspected ACS had a different final diagnosis. Among those with confirmed ACS, the use of CAG, PCI, CABG, and effective medications is rational. Outcome in NSTEMI patients was equivalent to those in STEMI patients, mainly due to the high-risk population in this group.
dcterms:title
The incidence and outcomes of acute coronary syndromes in a central European country: Results of the CZECH-2 registry The incidence and outcomes of acute coronary syndromes in a central European country: Results of the CZECH-2 registry
skos:prefLabel
The incidence and outcomes of acute coronary syndromes in a central European country: Results of the CZECH-2 registry The incidence and outcomes of acute coronary syndromes in a central European country: Results of the CZECH-2 registry
skos:notation
RIV/00216208:11120/14:43908256!RIV15-MSM-11120___
n3:aktivita
n11:I n11:N
n3:aktivity
I, N
n3:cisloPeriodika
2
n3:dodaniDat
n9:2015
n3:domaciTvurceVysledku
n7:9830758 n7:1304585 n7:2228734
n3:druhVysledku
n14:J
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n8:predkladatel
n3:idSjednocenehoVysledku
21113
n3:idVysledku
RIV/00216208:11120/14:43908256
n3:jazykVysledku
n16:eng
n3:klicovaSlova
registry; outcome; incidence; acute coronary syndrome
n3:klicoveSlovo
n4:incidence n4:outcome n4:registry n4:acute%20coronary%20syndrome
n3:kodStatuVydavatele
IE - Irsko
n3:kontrolniKodProRIV
[155A1F391AA5]
n3:nazevZdroje
International Journal of Cardiology
n3:obor
n15:FA
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
8
n3:rokUplatneniVysledku
n9:2014
n3:svazekPeriodika
173
n3:tvurceVysledku
Widimský, Petr Toušek, Petr Pešl, Ladislav
n3:wos
000334508200020
s:issn
0167-5273
s:numberOfPages
5
n12:doi
10.1016/j.ijcard.2014.02.013
n17:organizacniJednotka
11120