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Statements

Subject Item
n2:RIV%2F00216208%3A11120%2F13%3A43907489%21RIV14-MSM-11120___
rdf:type
n5:Vysledek skos:Concept
dcterms:description
This study deals with the monitoring of the plasmatic level of malondialdehyde, as the main indicator of oxidative damage to biomembranes. Malondialdehyde is determined by HPLC after derivatization employing 2,4-dinitrophenylhydrazine. A clinical study involving 20 female patients suffering from ovarian and endometrical carcinomas has demonstrated elevated levels of malondialdehyde (10.1 ± 1.1 µM), compared with the control group (7.5 ± 2.7 µM). It has been further verified that surgical removal of the tumor leads to an additional increase in the plasmatic malondialdehyde content. This unfavourable situation can be effectively eliminated by administration of a single dose of vitamin E prior to surgery. This study deals with the monitoring of the plasmatic level of malondialdehyde, as the main indicator of oxidative damage to biomembranes. Malondialdehyde is determined by HPLC after derivatization employing 2,4-dinitrophenylhydrazine. A clinical study involving 20 female patients suffering from ovarian and endometrical carcinomas has demonstrated elevated levels of malondialdehyde (10.1 ± 1.1 µM), compared with the control group (7.5 ± 2.7 µM). It has been further verified that surgical removal of the tumor leads to an additional increase in the plasmatic malondialdehyde content. This unfavourable situation can be effectively eliminated by administration of a single dose of vitamin E prior to surgery.
dcterms:title
The effect of vitamin E on plasmatic malondialdehyde levels during surgical removal of ovarian and endometrial carcinomas The effect of vitamin E on plasmatic malondialdehyde levels during surgical removal of ovarian and endometrial carcinomas
skos:prefLabel
The effect of vitamin E on plasmatic malondialdehyde levels during surgical removal of ovarian and endometrial carcinomas The effect of vitamin E on plasmatic malondialdehyde levels during surgical removal of ovarian and endometrial carcinomas
skos:notation
RIV/00216208:11120/13:43907489!RIV14-MSM-11120___
n5:predkladatel
n13:orjk%3A11120
n3:aktivita
n8:I
n3:aktivity
I
n3:cisloPeriodika
4
n3:dodaniDat
n12:2014
n3:domaciTvurceVysledku
n4:4939786 n4:5923492 n4:2944146 n4:4477545 n4:6738796
n3:druhVysledku
n6:J
n3:duvernostUdaju
n14:S
n3:entitaPredkladatele
n10:predkladatel
n3:idSjednocenehoVysledku
71829
n3:idVysledku
RIV/00216208:11120/13:43907489
n3:jazykVysledku
n18:eng
n3:klicovaSlova
Gynaecology.; Vitamin E; Malondialdehyde; Lipid peroxidation; Cancer
n3:klicoveSlovo
n9:Vitamin%20E n9:Gynaecology. n9:Lipid%20peroxidation n9:Malondialdehyde n9:Cancer
n3:kodStatuVydavatele
CA - Kanada
n3:kontrolniKodProRIV
[709C76F0D9B1]
n3:nazevZdroje
European Journal of Gynaecological Oncology
n3:obor
n17:FK
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
5
n3:rokUplatneniVysledku
n12:2013
n3:svazekPeriodika
34
n3:tvurceVysledku
Rokyta, Richard Samec, Martin Matějčková, Jana Samcová, Eva Tůma, Petr
s:issn
0392-2936
s:numberOfPages
3
n16:organizacniJednotka
11120