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Statements

Subject Item
n2:RIV%2F00216208%3A11120%2F10%3A43906856%21RIV13-MSM-11120___
rdf:type
skos:Concept n10:Vysledek
dcterms:description
Multiple psychotropic medications are routinely prescribed to treat bipolar disorder, creating complex medication regimens. This study investigated whether the daily number of psychotropic medications or the daily number of pills were associated with self-reported adherence with taking a mood stabilizer. Methods Patients self-reported their mood and medications taken daily for about 6 months. Adherence was defined as taking at least one pill of any mood stabilizer daily. Univariate general linear models (GLMs) were used to estimate if adherence was associated with the number of daily medications and the number of pills, controlling for age. The association between mean daily dosage of mood stabilizer and adherence was also estimated using a GLM. Results Three hundred and twelve patients (mean age 38.4 +/- 10.9 years) returned 58,106 days of data and took a mean of 3.1 +/- 1.6 psychotropic medications daily (7.0 +/- 4.2 pills). No significant association was found between either the daily number of medications or the daily number of pills and adherence. For most mood stabilizers, patients with lower adherence took a significantly smaller mean daily dosage. Conclusions The number of concurrent psychotropic medications may not be associated with adherence in bipolar disorder. Patients with lower adherence may be taking smaller dosages of mood stabilizers. Multiple psychotropic medications are routinely prescribed to treat bipolar disorder, creating complex medication regimens. This study investigated whether the daily number of psychotropic medications or the daily number of pills were associated with self-reported adherence with taking a mood stabilizer. Methods Patients self-reported their mood and medications taken daily for about 6 months. Adherence was defined as taking at least one pill of any mood stabilizer daily. Univariate general linear models (GLMs) were used to estimate if adherence was associated with the number of daily medications and the number of pills, controlling for age. The association between mean daily dosage of mood stabilizer and adherence was also estimated using a GLM. Results Three hundred and twelve patients (mean age 38.4 +/- 10.9 years) returned 58,106 days of data and took a mean of 3.1 +/- 1.6 psychotropic medications daily (7.0 +/- 4.2 pills). No significant association was found between either the daily number of medications or the daily number of pills and adherence. For most mood stabilizers, patients with lower adherence took a significantly smaller mean daily dosage. Conclusions The number of concurrent psychotropic medications may not be associated with adherence in bipolar disorder. Patients with lower adherence may be taking smaller dosages of mood stabilizers.
dcterms:title
The association between concurrent psychotropic medications and self-reported adherence with taking a mood stabilizer in bipolar disorder The association between concurrent psychotropic medications and self-reported adherence with taking a mood stabilizer in bipolar disorder
skos:prefLabel
The association between concurrent psychotropic medications and self-reported adherence with taking a mood stabilizer in bipolar disorder The association between concurrent psychotropic medications and self-reported adherence with taking a mood stabilizer in bipolar disorder
skos:notation
RIV/00216208:11120/10:43906856!RIV13-MSM-11120___
n3:aktivita
n16:N
n3:aktivity
N
n3:cisloPeriodika
1
n3:dodaniDat
n7:2013
n3:domaciTvurceVysledku
n14:8421382
n3:druhVysledku
n17:J
n3:duvernostUdaju
n12:S
n3:entitaPredkladatele
n13:predkladatel
n3:idSjednocenehoVysledku
247950
n3:idVysledku
RIV/00216208:11120/10:43906856
n3:jazykVysledku
n4:eng
n3:klicovaSlova
mood stabilizer; polypharmacy; adherence; bipolar disorder
n3:klicoveSlovo
n8:polypharmacy n8:adherence n8:mood%20stabilizer n8:bipolar%20disorder
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[2F7B68AADA30]
n3:nazevZdroje
Human Psychopharmacology - Clinical and Experimental
n3:obor
n11:FL
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
11
n3:rokUplatneniVysledku
n7:2010
n3:svazekPeriodika
25
n3:tvurceVysledku
Alda, Martin
n3:wos
000274802100005
s:issn
0885-6222
s:numberOfPages
8
n15:doi
10.1002/hup.1077
n18:organizacniJednotka
11120