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Statements

Subject Item
n2:RIV%2F00216208%3A11120%2F10%3A00002409%21RIV11-GA0-11120___
rdf:type
skos:Concept n19:Vysledek
dcterms:description
The effect of psychostimulants on social behavior still remains unclear. Therefore the aim of the present study was to assess the effect of low doses of methamphetamine (MA) on social interaction (SI) in adult male rats. Rats were tested in three environmental conditions: (1) dimly lit, familiar environment, (2) dimly lit, unfamiliar environment and (3) intensely lit, unfamiliar environment considered to be low, middle and high stress, respectively. In each condition different set of animals was used. Rats were always divided into five groups. Control (without injection), saline (with 1 ml/kg saline injection) and three MA groups (doses: 0.5, 1 and 1.5mg/kg). Injections were applied 30 min prior to testing. Always a pair of unfamiliar rats of the same treatment group was tested. Their behavior was video recorded for 5 min in an open field. Times spent by SI (following, climbing, genital investigation, etc.) and non-social behavior (locomotion, rearing) were analyzed using a two-way ANOVA (drug treatme The effect of psychostimulants on social behavior still remains unclear. Therefore the aim of the present study was to assess the effect of low doses of methamphetamine (MA) on social interaction (SI) in adult male rats. Rats were tested in three environmental conditions: (1) dimly lit, familiar environment, (2) dimly lit, unfamiliar environment and (3) intensely lit, unfamiliar environment considered to be low, middle and high stress, respectively. In each condition different set of animals was used. Rats were always divided into five groups. Control (without injection), saline (with 1 ml/kg saline injection) and three MA groups (doses: 0.5, 1 and 1.5mg/kg). Injections were applied 30 min prior to testing. Always a pair of unfamiliar rats of the same treatment group was tested. Their behavior was video recorded for 5 min in an open field. Times spent by SI (following, climbing, genital investigation, etc.) and non-social behavior (locomotion, rearing) were analyzed using a two-way ANOVA (drug treatme
dcterms:title
The effect of methamphetamine on social interaction of adult male rats The effect of methamphetamine on social interaction of adult male rats
skos:prefLabel
The effect of methamphetamine on social interaction of adult male rats The effect of methamphetamine on social interaction of adult male rats
skos:notation
RIV/00216208:11120/10:00002409!RIV11-GA0-11120___
n3:aktivita
n4:Z n4:P
n3:aktivity
P(1M0517), P(GAP303/10/0580), Z(MSM0021620816)
n3:cisloPeriodika
2
n3:dodaniDat
n5:2011
n3:domaciTvurceVysledku
n12:1128574 n12:1957341 n12:4711491 n12:1027980 n12:6841910 n12:6877141
n3:druhVysledku
n18:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
256058
n3:idVysledku
RIV/00216208:11120/10:00002409
n3:jazykVysledku
n15:eng
n3:klicovaSlova
Methamphetamine; social behavior; stress environment condition
n3:klicoveSlovo
n6:Methamphetamine n6:stress%20environment%20condition n6:social%20behavior
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[F14FFCB62E89]
n3:nazevZdroje
Behavioural Brain Research
n3:obor
n11:FH
n3:pocetDomacichTvurcuVysledku
6
n3:pocetTvurcuVysledku
6
n3:projekt
n13:1M0517 n13:GAP303%2F10%2F0580
n3:rokUplatneniVysledku
n5:2010
n3:svazekPeriodika
214
n3:tvurceVysledku
Hrubá, Lenka Deykun, Kateryna Mikulecká, Anna Schutová, Barbora Šlamberová, Romana Pometlová, Marie
n3:wos
000281318700034
n3:zamer
n17:MSM0021620816
s:issn
0166-4328
s:numberOfPages
5
n14:organizacniJednotka
11120