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Statements

Subject Item
n2:RIV%2F00216208%3A11120%2F08%3A00003115%21RIV12-MSM-11120___
rdf:type
skos:Concept n17:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.1007/s00406-008-3002-1
dcterms:description
In the past few years several papers have reported critically on the risk of suicidal thoughts and behaviour associated with antidepressants, primarily SSRIs. The risk-benefit ratio of antidepressant (AD) treatment has been questioned especially in children and adolescents. The critical publications led to warnings being issued by regulatory authorities such as the FDA, MHRA and EMEA and stimulated new research activity in this field. However, potential harmful effects of antidepressants on suicidality are difficult to investigate in empirical studies because these have several methodological limitations. Randomised controlled trials (RCTs) are the most reliable way to test the hypothesis that AD have such side effects. In addition to meta-analyses of RCTs, complementary research methods should be applied to obtain the most comprehensive information. We undertook a comprehensive review of publications related to the topics ADs, suicide, suicidality, suicidal behaviour and aggression. Based on this com In the past few years several papers have reported critically on the risk of suicidal thoughts and behaviour associated with antidepressants, primarily SSRIs. The risk-benefit ratio of antidepressant (AD) treatment has been questioned especially in children and adolescents. The critical publications led to warnings being issued by regulatory authorities such as the FDA, MHRA and EMEA and stimulated new research activity in this field. However, potential harmful effects of antidepressants on suicidality are difficult to investigate in empirical studies because these have several methodological limitations. Randomised controlled trials (RCTs) are the most reliable way to test the hypothesis that AD have such side effects. In addition to meta-analyses of RCTs, complementary research methods should be applied to obtain the most comprehensive information. We undertook a comprehensive review of publications related to the topics ADs, suicide, suicidality, suicidal behaviour and aggression. Based on this com
dcterms:title
Do SSRIs or antidepressants in general increase suicidality? WPA Section on Pharmacopsychiatry: consensus statement Do SSRIs or antidepressants in general increase suicidality? WPA Section on Pharmacopsychiatry: consensus statement
skos:prefLabel
Do SSRIs or antidepressants in general increase suicidality? WPA Section on Pharmacopsychiatry: consensus statement Do SSRIs or antidepressants in general increase suicidality? WPA Section on Pharmacopsychiatry: consensus statement
skos:notation
RIV/00216208:11120/08:00003115!RIV12-MSM-11120___
n5:aktivita
n8:N
n5:aktivity
N
n5:cisloPeriodika
Suppl. 3
n5:dodaniDat
n15:2012
n5:domaciTvurceVysledku
n9:1371576
n5:druhVysledku
n11:J
n5:duvernostUdaju
n19:S
n5:entitaPredkladatele
n18:predkladatel
n5:idSjednocenehoVysledku
364067
n5:idVysledku
RIV/00216208:11120/08:00003115
n5:jazykVysledku
n14:eng
n5:klicovaSlova
antidepressants; suicidality
n5:klicoveSlovo
n13:antidepressants n13:suicidality
n5:kodStatuVydavatele
DE - Spolková republika Německo
n5:kontrolniKodProRIV
[01C53B72CEAE]
n5:nazevZdroje
European Archives of Psychiatry and Clinical Neuroscience
n5:obor
n10:FL
n5:pocetDomacichTvurcuVysledku
1
n5:pocetTvurcuVysledku
10
n5:rokUplatneniVysledku
n15:2008
n5:svazekPeriodika
258
n5:tvurceVysledku
Höschl, Cyril Möller, Hans-Jürgen
n5:wos
000258494300001
s:issn
0940-1334
s:numberOfPages
21
n7:doi
10.1007/s00406-008-3002-1
n12:organizacniJednotka
11120