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Statements

Subject Item
n2:RIV%2F00216208%3A11120%2F05%3A00009566%21RIV06-MZ0-11120___
rdf:type
n5:Vysledek skos:Concept
dcterms:description
The death induced by the taxanes in the studied brest cancer cells can be characterized as an apoptosis-like death, including caspase-3 and caspase-9 activation but not oligonucleosomal DNA fragmentation. However, the mechanism of death induction by the taxanes in sensitive MDA-MB-435 cells and resistant NCI-ADR-RES cells differ. Cytochrome c is released from the mitochondria in resistant but not in sensitive cells. The death induced by the taxanes in the studied brest cancer cells can be characterized as an apoptosis-like death, including caspase-3 and caspase-9 activation but not oligonucleosomal DNA fragmentation. However, the mechanism of death induction by the taxanes in sensitive MDA-MB-435 cells and resistant NCI-ADR-RES cells differ. Cytochrome c is released from the mitochondria in resistant but not in sensitive cells. Smrt indukovanou taxany ve studovaných buňkách nádoru prsu lze charakterizovat jako apoptóze podobnou smrt, která zahrnuje aktivaci kaspázy 3 a kaspázy 9, ale nezahrnuje oligonukleozomální fragmentaci DNA. Mechanismus indukce smrti taxany u senzitivních MDA-MB-435 buněk a rezistentních NCI-ADR-RES buněk se však liší. Cytochrom c se uvolňuje zmitochondrií vrezistentních, ale ne v senzitivních buňkách.
dcterms:title
Buněčná smrt indukovaná taxany vbuňkách nádoru prsu: cytochrom c se uvolňuje vrezistentních, ale ne v senzitivních buňkách Cell Death Induced by Taxanes in Brest Cancer Cells: Cytochrome c is Released in Resistant but not in Sensitive Cells Cell Death Induced by Taxanes in Brest Cancer Cells: Cytochrome c is Released in Resistant but not in Sensitive Cells
skos:prefLabel
Cell Death Induced by Taxanes in Brest Cancer Cells: Cytochrome c is Released in Resistant but not in Sensitive Cells Cell Death Induced by Taxanes in Brest Cancer Cells: Cytochrome c is Released in Resistant but not in Sensitive Cells Buněčná smrt indukovaná taxany vbuňkách nádoru prsu: cytochrom c se uvolňuje vrezistentních, ale ne v senzitivních buňkách
skos:notation
RIV/00216208:11120/05:00009566!RIV06-MZ0-11120___
n3:strany
4215;4224
n3:aktivita
n16:P
n3:aktivity
P(NL7567)
n3:cisloPeriodika
6B
n3:dodaniDat
n13:2006
n3:domaciTvurceVysledku
n14:1758330
n3:druhVysledku
n18:J
n3:duvernostUdaju
n7:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
514596
n3:idVysledku
RIV/00216208:11120/05:00009566
n3:jazykVysledku
n12:eng
n3:klicovaSlova
Death; Induced; Taxanes; Brest; Cancer; Cells; Cytochrome; Released; Resistant; Sensitive; Cells
n3:klicoveSlovo
n11:Taxanes n11:Cytochrome n11:Resistant n11:Released n11:Cancer n11:Induced n11:Sensitive n11:Death n11:Cells n11:Brest
n3:kodStatuVydavatele
GR - Řecká republika
n3:kontrolniKodProRIV
[E726279D1903]
n3:nazevZdroje
Anticancer Research
n3:obor
n15:EB
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
6
n3:projekt
n4:NL7567
n3:rokUplatneniVysledku
n13:2005
n3:svazekPeriodika
25
n3:tvurceVysledku
Kovář, Jan
s:issn
0250-7005
s:numberOfPages
10
n10:organizacniJednotka
11120