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Statements

Subject Item
n2:RIV%2F00216208%3A11120%2F01%3A00003666%21RIV12-MSM-11120___
rdf:type
skos:Concept n15:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.1046/j.1468-3083.2001.00346.x
dcterms:description
A 45-year-old woman had symmetrical livid plaques with yellowish hyperkeratoses for 5 years, which progressed on to the fingers and toes and on the soles of the feet. Two years later creamy, whitish areas and maceration appeared on the buccal mucosa and the lips. A skin biopsy revealed massive collagen hyaline degeneration in the perivascular area, hyperkeratosis and hypergranulosis, small lymphocyte infiltrates with several melanophages and extravasates of erythrocytes in the upper corium. in perivascular areas and hydropic degeneration of basal keratinocytes. The findings using direct immunofluorescence were compatible with lupus erythematosus (LE). Laboratory investigation showed a slight leucopenia and thrombopenia, a slightly elevated erythrocyte sedimentation rate, hypocomplementaernia C3 and C4, a high titre of rheumatoid factor and antinuclear antibodies positivity of extractable nuclear antigen. The results reflected probably the development of a systemic form of the disease. The patient was A 45-year-old woman had symmetrical livid plaques with yellowish hyperkeratoses for 5 years, which progressed on to the fingers and toes and on the soles of the feet. Two years later creamy, whitish areas and maceration appeared on the buccal mucosa and the lips. A skin biopsy revealed massive collagen hyaline degeneration in the perivascular area, hyperkeratosis and hypergranulosis, small lymphocyte infiltrates with several melanophages and extravasates of erythrocytes in the upper corium. in perivascular areas and hydropic degeneration of basal keratinocytes. The findings using direct immunofluorescence were compatible with lupus erythematosus (LE). Laboratory investigation showed a slight leucopenia and thrombopenia, a slightly elevated erythrocyte sedimentation rate, hypocomplementaernia C3 and C4, a high titre of rheumatoid factor and antinuclear antibodies positivity of extractable nuclear antigen. The results reflected probably the development of a systemic form of the disease. The patient was
dcterms:title
Verrucous form of chilblain lupus erythematosus Verrucous form of chilblain lupus erythematosus
skos:prefLabel
Verrucous form of chilblain lupus erythematosus Verrucous form of chilblain lupus erythematosus
skos:notation
RIV/00216208:11120/01:00003666!RIV12-MSM-11120___
n4:aktivita
n20:Z
n4:aktivity
Z(AV0Z5039906), Z(MSM 111200002)
n4:cisloPeriodika
5
n4:dodaniDat
n10:2012
n4:domaciTvurceVysledku
n9:7449186
n4:druhVysledku
n14:J
n4:duvernostUdaju
n19:S
n4:entitaPredkladatele
n13:predkladatel
n4:idSjednocenehoVysledku
700228
n4:idVysledku
RIV/00216208:11120/01:00003666
n4:jazykVysledku
n11:eng
n4:klicovaSlova
chilblain lupus; collagen hyalinization; verrucous form
n4:klicoveSlovo
n12:chilblain%20lupus n12:verrucous%20form n12:collagen%20hyalinization
n4:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n4:kontrolniKodProRIV
[A6705B071415]
n4:nazevZdroje
Journal of the European Academy of Dermatology and Venereology
n4:obor
n17:FO
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
5
n4:rokUplatneniVysledku
n10:2001
n4:svazekPeriodika
15
n4:tvurceVysledku
Pock, L. Mandys, Václav
n4:wos
000172032900018
n4:zamer
n5:MSM%20111200002 n5:AV0Z5039906
s:issn
0926-9959
s:numberOfPages
4
n7:doi
10.1046/j.1468-3083.2001.00346.x
n8:organizacniJednotka
11120