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Statements

Subject Item
n2:RIV%2F00216208%3A11120%2F00%3A00003745%21RIV12-MSM-11120___
rdf:type
n13:Vysledek skos:Concept
rdfs:seeAlso
http://dx.doi.org/10.1016/S0165-3806(00)00031-6
dcterms:description
Bicuculline was used to investigate seizure susceptibility in pre- and peripubertal male and female rats exposed prenatally to morphine. Morphine-exposed males showed increased seizure susceptibility at prepubertal and decreased susceptibility at peripubertal ages. There was no difference in seizure susceptibility in morphine-exposed females at either age. Therefore, the present data suggest that males are more vulnerable than females to morphine-induced insults during prenatal brain development. Bicuculline was used to investigate seizure susceptibility in pre- and peripubertal male and female rats exposed prenatally to morphine. Morphine-exposed males showed increased seizure susceptibility at prepubertal and decreased susceptibility at peripubertal ages. There was no difference in seizure susceptibility in morphine-exposed females at either age. Therefore, the present data suggest that males are more vulnerable than females to morphine-induced insults during prenatal brain development.
dcterms:title
Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner
skos:prefLabel
Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner Prenatal morphine exposure alters susceptibility to bicuculline seizures in a sex- and age-specific manner
skos:notation
RIV/00216208:11120/00:00003745!RIV12-MSM-11120___
n3:aktivita
n9:Z
n3:aktivity
Z(MSM 111200005)
n3:cisloPeriodika
1
n3:dodaniDat
n12:2012
n3:domaciTvurceVysledku
n10:4744934 n10:6877141
n3:druhVysledku
n20:J
n3:duvernostUdaju
n4:S
n3:entitaPredkladatele
n11:predkladatel
n3:idSjednocenehoVysledku
722905
n3:idVysledku
RIV/00216208:11120/00:00003745
n3:jazykVysledku
n17:eng
n3:klicovaSlova
Epilepsy; Prenatal drug exposure; Opiates; Development; Gender
n3:klicoveSlovo
n7:Opiates n7:Prenatal%20drug%20exposure n7:Development n7:Gender n7:Epilepsy
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[06CB752B6833]
n3:nazevZdroje
Developmental Brain Research
n3:obor
n16:ED
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
4
n3:rokUplatneniVysledku
n12:2000
n3:svazekPeriodika
121
n3:tvurceVysledku
Šlamberová, Romana Schindler, C. J. Velíšková, Jana Vathy, Ilona
n3:wos
000087406900014
n3:zamer
n18:MSM%20111200005
s:issn
0165-3806
s:numberOfPages
4
n19:doi
10.1016/S0165-3806(00)00031-6
n5:organizacniJednotka
11120