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Statements

Subject Item
n2:RIV%2F00216208%3A11110%2F14%3A10292401%21RIV15-MSM-11110___
rdf:type
n10:Vysledek skos:Concept
rdfs:seeAlso
http://dx.doi.org/10.1002/elps.201400046
dcterms:description
DNA samples of 523 unrelated anonymized individuals (307 males and 216 females) born and living in the Czech Republic were genotyped using Investigator (R) Argus X-12 system in the following loci localized in four linkage groups: DXS10148, DXS10135, DXS8378, DXS7132, DXS10079, DXS10074, DXS10103, HPRTB, DXS10101, DXS10146, DXS10134, DXS742. Haplotype frequencies were calculated for each LG (Linkage Group). The frequency of most common haplotype was 0.016, 0.036, 0.042, and 0.023 for LG1, LG2, LG3, and LG4, respectively. The combined power of discrimination was more than 0.999999999 both for female and male samples. The mean exclusion chance was 0.99999999 (trios) and 0.999999 (duos). Informativity and suitability of Investigator (R) Argus X-12 for kinship determination was assessed by computing in several female-female duos using LR (Likelihood Ratio) determination for autosomal STR (PowerPlex ESI-17), linked (Investigator (R) Argus X-12 system), and unlinked (X-STR Decaplex) X-STR kits. Investigator (R) Argus X-12 proved to be very useful for sibship determination, since its LR values were relatively similar to LR for autosomal STR kit. This work presents the first population data for Investigator (R) Argus X-12 system in the Czech Republic. DNA samples of 523 unrelated anonymized individuals (307 males and 216 females) born and living in the Czech Republic were genotyped using Investigator (R) Argus X-12 system in the following loci localized in four linkage groups: DXS10148, DXS10135, DXS8378, DXS7132, DXS10079, DXS10074, DXS10103, HPRTB, DXS10101, DXS10146, DXS10134, DXS742. Haplotype frequencies were calculated for each LG (Linkage Group). The frequency of most common haplotype was 0.016, 0.036, 0.042, and 0.023 for LG1, LG2, LG3, and LG4, respectively. The combined power of discrimination was more than 0.999999999 both for female and male samples. The mean exclusion chance was 0.99999999 (trios) and 0.999999 (duos). Informativity and suitability of Investigator (R) Argus X-12 for kinship determination was assessed by computing in several female-female duos using LR (Likelihood Ratio) determination for autosomal STR (PowerPlex ESI-17), linked (Investigator (R) Argus X-12 system), and unlinked (X-STR Decaplex) X-STR kits. Investigator (R) Argus X-12 proved to be very useful for sibship determination, since its LR values were relatively similar to LR for autosomal STR kit. This work presents the first population data for Investigator (R) Argus X-12 system in the Czech Republic.
dcterms:title
Investigator (R) Argus X-12 study on the population of Czech Republic: Comparison of linked and unlinked X-STRs for kinship analysis Investigator (R) Argus X-12 study on the population of Czech Republic: Comparison of linked and unlinked X-STRs for kinship analysis
skos:prefLabel
Investigator (R) Argus X-12 study on the population of Czech Republic: Comparison of linked and unlinked X-STRs for kinship analysis Investigator (R) Argus X-12 study on the population of Czech Republic: Comparison of linked and unlinked X-STRs for kinship analysis
skos:notation
RIV/00216208:11110/14:10292401!RIV15-MSM-11110___
n3:aktivita
n19:V
n3:aktivity
V
n3:cisloPeriodika
14
n3:dodaniDat
n7:2015
n3:domaciTvurceVysledku
n13:5207517
n3:druhVysledku
n17:J
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n11:predkladatel
n3:idSjednocenehoVysledku
22787
n3:idVysledku
RIV/00216208:11110/14:10292401
n3:jazykVysledku
n12:eng
n3:klicovaSlova
X-STR Decaplex; X-STR; Kinship analysis; Investigator (R) Argus X-12; Forensic genetics
n3:klicoveSlovo
n6:X-STR n6:Investigator%20%28R%29%20Argus%20X-12 n6:Kinship%20analysis n6:Forensic%20genetics n6:X-STR%20Decaplex
n3:kodStatuVydavatele
DE - Spolková republika Německo
n3:kontrolniKodProRIV
[98B52318C1C0]
n3:nazevZdroje
Electrophoresis
n3:obor
n18:EB
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
4
n3:rokUplatneniVysledku
n7:2014
n3:svazekPeriodika
35
n3:tvurceVysledku
Zidkova, Anastassiya Hořínek, Aleš Capek, Pavel Coufalova, Pavla
n3:wos
000339661300008
s:issn
0173-0835
s:numberOfPages
4
n8:doi
10.1002/elps.201400046
n16:organizacniJednotka
11110