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Statements

Subject Item
n2:RIV%2F00216208%3A11110%2F14%3A10287038%21RIV15-MSM-11110___
rdf:type
skos:Concept n18:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.4149/endo_2014_02_55
dcterms:description
Objective: To assess the incidence of parathyroid glands hyperplasia or adenoma in patients with various stages of chronic renal insufficiency using 99mTc-methoxyisobutylisonitrile (MIBI) SPECT and 3D subtraction technique with 99mTc-pertechnetate (Tc). Subjects and methods: 61 patients underwent hybrid SPECT with low-dose CT of the parathyroid glands and thyroid SPECT scintigraphy. 36 patients were with chronic kidney disease (CKD) without renal failure (RF) and 25 patients undergoing peritoneal dialysis or hemodialysis. In each patient, two SPECT studies were performed - an early and a late one with low dose CT with MIBI injection. Additional SPECT was performed on another day with Tc. Results: From all 61 patients, 40/61(66%) findings were positive, 7/61(12%) findings were inconclusive and 14/61(23%) findings were negative. Solitary lesions were detected in 22 patients. More than one lesion was found in 18 patients. Conclusion: The incidence of secondary hyperparathyroidism was detected in 40/61 patients (66%) with chronic kidney disease using scintigraphy and 16 patients (40%) from them underwent surgery. MIBI SPECT/low dose CT with 3D dual - tracer subtraction (MIBI-Tc) method is an effective tool for preoperative detection of the parathyroid glands hyperplasia or adenoma. Objective: To assess the incidence of parathyroid glands hyperplasia or adenoma in patients with various stages of chronic renal insufficiency using 99mTc-methoxyisobutylisonitrile (MIBI) SPECT and 3D subtraction technique with 99mTc-pertechnetate (Tc). Subjects and methods: 61 patients underwent hybrid SPECT with low-dose CT of the parathyroid glands and thyroid SPECT scintigraphy. 36 patients were with chronic kidney disease (CKD) without renal failure (RF) and 25 patients undergoing peritoneal dialysis or hemodialysis. In each patient, two SPECT studies were performed - an early and a late one with low dose CT with MIBI injection. Additional SPECT was performed on another day with Tc. Results: From all 61 patients, 40/61(66%) findings were positive, 7/61(12%) findings were inconclusive and 14/61(23%) findings were negative. Solitary lesions were detected in 22 patients. More than one lesion was found in 18 patients. Conclusion: The incidence of secondary hyperparathyroidism was detected in 40/61 patients (66%) with chronic kidney disease using scintigraphy and 16 patients (40%) from them underwent surgery. MIBI SPECT/low dose CT with 3D dual - tracer subtraction (MIBI-Tc) method is an effective tool for preoperative detection of the parathyroid glands hyperplasia or adenoma.
dcterms:title
The role of 99mTc-MIBI SPECT/low dose CT with 3D subtraction in patients with secondary hyperparathyroidism due to chronic kidney disease The role of 99mTc-MIBI SPECT/low dose CT with 3D subtraction in patients with secondary hyperparathyroidism due to chronic kidney disease
skos:prefLabel
The role of 99mTc-MIBI SPECT/low dose CT with 3D subtraction in patients with secondary hyperparathyroidism due to chronic kidney disease The role of 99mTc-MIBI SPECT/low dose CT with 3D subtraction in patients with secondary hyperparathyroidism due to chronic kidney disease
skos:notation
RIV/00216208:11110/14:10287038!RIV15-MSM-11110___
n3:aktivita
n4:V
n3:aktivity
V
n3:cisloPeriodika
2
n3:dodaniDat
n5:2015
n3:domaciTvurceVysledku
n6:8057230 n6:5186617 n6:5273234 n6:6425917
n3:druhVysledku
n11:J
n3:duvernostUdaju
n8:S
n3:entitaPredkladatele
n19:predkladatel
n3:idSjednocenehoVysledku
43219
n3:idVysledku
RIV/00216208:11110/14:10287038
n3:jazykVysledku
n16:eng
n3:klicovaSlova
disease.; kidney; chronic; due; hyperparathyroidism; secondary; with; patients; subtraction; dose; SPECT/low; 99mTc-MIBI; role
n3:klicoveSlovo
n7:99mTc-MIBI n7:disease. n7:chronic n7:role n7:patients n7:secondary n7:SPECT%2Flow n7:due n7:hyperparathyroidism n7:with n7:kidney n7:dose n7:subtraction
n3:kodStatuVydavatele
SK - Slovenská republika
n3:kontrolniKodProRIV
[49D6309E0334]
n3:nazevZdroje
Endocrine Regulations
n3:obor
n14:FE
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
4
n3:rokUplatneniVysledku
n5:2014
n3:svazekPeriodika
48
n3:tvurceVysledku
Adámek, Svatopluk Kubinyi, Jozef Trnka, Jiří Chroustová, Daniela
s:issn
1210-0668
s:numberOfPages
9
n12:doi
10.4149/endo_2014_02_55
n15:organizacniJednotka
11110