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Statements

Subject Item
n2:RIV%2F00216208%3A11110%2F14%3A10286785%21RIV15-MSM-11110___
rdf:type
skos:Concept n12:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.1097/EJA.0000000000000100
dcterms:description
BACKGROUND Regular endotracheal tube cuff monitoring may prevent silent aspiration. OBJECTIVES We hypothesised that active management of the cuff of the tracheal tube during deep hypothermic cardiac arrest would reduce silent subglottic aspiration. We also determined to study its effect on postoperative mechanical ventilation and the incidence of postoperative positive tracheal cultures. DESIGN A randomised clinical trial. SETTING The study was conducted in a University Teaching Hospital from September 2008 to November 2009. PATIENTS Twenty-four patients undergoing elective pulmonary endarterectomy were included in the study. MAIN OUTCOME MEASURES The primary aim of this study was to determine the incidence of silent aspiration. Secondary outcomes included duration of postoperative mechanical ventilation of the lungs and incidence of positive culture of tracheal aspirate. RESULTS Active cuff management patients were younger than controls (51.2 +/- 11.6 vs. 63.2 +/- 9 years, P = 0.028), but otherwise the two groups were similar. The primary endpoint was reached because we showed that silent aspiration was significantly less frequent in the study group (0/12 vs. 8/12 patients, P = 0.001). Significantly lower intracuff pressures were measured in the control group patients at several timepoints during cooling, just before hypothermic arrest and at all timepoints during rewarming. CONCLUSION We recommend that the cuff of the tracheal tube should be checked regularly during surgery under deep hypothermia, and the cuff pressure adjusted as required. BACKGROUND Regular endotracheal tube cuff monitoring may prevent silent aspiration. OBJECTIVES We hypothesised that active management of the cuff of the tracheal tube during deep hypothermic cardiac arrest would reduce silent subglottic aspiration. We also determined to study its effect on postoperative mechanical ventilation and the incidence of postoperative positive tracheal cultures. DESIGN A randomised clinical trial. SETTING The study was conducted in a University Teaching Hospital from September 2008 to November 2009. PATIENTS Twenty-four patients undergoing elective pulmonary endarterectomy were included in the study. MAIN OUTCOME MEASURES The primary aim of this study was to determine the incidence of silent aspiration. Secondary outcomes included duration of postoperative mechanical ventilation of the lungs and incidence of positive culture of tracheal aspirate. RESULTS Active cuff management patients were younger than controls (51.2 +/- 11.6 vs. 63.2 +/- 9 years, P = 0.028), but otherwise the two groups were similar. The primary endpoint was reached because we showed that silent aspiration was significantly less frequent in the study group (0/12 vs. 8/12 patients, P = 0.001). Significantly lower intracuff pressures were measured in the control group patients at several timepoints during cooling, just before hypothermic arrest and at all timepoints during rewarming. CONCLUSION We recommend that the cuff of the tracheal tube should be checked regularly during surgery under deep hypothermia, and the cuff pressure adjusted as required.
dcterms:title
The effect of adjusting tracheal tube cuff pressure during deep hypothermic circulatory arrest A randomised trial The effect of adjusting tracheal tube cuff pressure during deep hypothermic circulatory arrest A randomised trial
skos:prefLabel
The effect of adjusting tracheal tube cuff pressure during deep hypothermic circulatory arrest A randomised trial The effect of adjusting tracheal tube cuff pressure during deep hypothermic circulatory arrest A randomised trial
skos:notation
RIV/00216208:11110/14:10286785!RIV15-MSM-11110___
n3:aktivita
n18:N
n3:aktivity
N
n3:cisloPeriodika
9
n3:dodaniDat
n16:2015
n3:domaciTvurceVysledku
n4:3253716 n4:5031028 n4:4379659 n4:1693980 n4:5624088 n4:6190898 n4:2143534 n4:7157991 n4:9548270
n3:druhVysledku
n19:J
n3:duvernostUdaju
n7:S
n3:entitaPredkladatele
n15:predkladatel
n3:idSjednocenehoVysledku
13099
n3:idVysledku
RIV/00216208:11110/14:10286785
n3:jazykVysledku
n13:eng
n3:klicovaSlova
pneumonia; cardiac-surgery
n3:klicoveSlovo
n17:pneumonia n17:cardiac-surgery
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[F39943222DA9]
n3:nazevZdroje
European Journal of Anaesthesiology
n3:obor
n11:FP
n3:pocetDomacichTvurcuVysledku
9
n3:pocetTvurcuVysledku
10
n3:rokUplatneniVysledku
n16:2014
n3:svazekPeriodika
31
n3:tvurceVysledku
Dohnalová, Alena Mlejnský, František Lindner, Jaroslav Kopecký, Petr Rulíšek, Jan Bláha, Jan Kunstýř, Jan Lipš, Michal Klein, Andrew A. Rubeš, David
n3:wos
000340360700003
s:issn
0265-0215
s:numberOfPages
5
n6:doi
10.1097/EJA.0000000000000100
n9:organizacniJednotka
11110