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Statements

Subject Item
n2:RIV%2F00216208%3A11110%2F13%3A10193047%21RIV14-MSM-11110___
rdf:type
n3:Vysledek skos:Concept
dcterms:description
The chapter summarizes information on the pathophysiology of mood disorders and biochemical mechanisms of action of antidepressants and mood stabilizers with focus on an endocannabinoid regulation of monoamines in depression and bipolar disorder. Leading role in neurochemistry and pathophysiology of mood disorders could be awarded to disturbed monoamine neurotransmission, dysfunction in energy metabolism of neurons, modulation of inflammatory and neuroendocrine pathways, and changes in activities of transcription factors, neurotrophic factors and other components involved in neuroplasticity. A role of endocannabinoid system in pathophysiology of mood disorders is supposed, but little known. In the light of new findings, there is potential for pharmacological regulation of endocannabinoid system in treatment of depressive and bipolar disorder. The chapter summarizes information on the pathophysiology of mood disorders and biochemical mechanisms of action of antidepressants and mood stabilizers with focus on an endocannabinoid regulation of monoamines in depression and bipolar disorder. Leading role in neurochemistry and pathophysiology of mood disorders could be awarded to disturbed monoamine neurotransmission, dysfunction in energy metabolism of neurons, modulation of inflammatory and neuroendocrine pathways, and changes in activities of transcription factors, neurotrophic factors and other components involved in neuroplasticity. A role of endocannabinoid system in pathophysiology of mood disorders is supposed, but little known. In the light of new findings, there is potential for pharmacological regulation of endocannabinoid system in treatment of depressive and bipolar disorder.
dcterms:title
Pathophysiology of Mood Disorders and Mechanisms of Action of Antidepressants and Mood Stabilizers Pathophysiology of Mood Disorders and Mechanisms of Action of Antidepressants and Mood Stabilizers
skos:prefLabel
Pathophysiology of Mood Disorders and Mechanisms of Action of Antidepressants and Mood Stabilizers Pathophysiology of Mood Disorders and Mechanisms of Action of Antidepressants and Mood Stabilizers
skos:notation
RIV/00216208:11110/13:10193047!RIV14-MSM-11110___
n3:predkladatel
n4:orjk%3A11110
n5:aktivita
n6:Z n6:I
n5:aktivity
I, Z(MSM0021620849)
n5:dodaniDat
n7:2014
n5:domaciTvurceVysledku
n15:7337280
n5:druhVysledku
n13:C
n5:duvernostUdaju
n21:S
n5:entitaPredkladatele
n17:predkladatel
n5:idSjednocenehoVysledku
95512
n5:idVysledku
RIV/00216208:11110/13:10193047
n5:jazykVysledku
n14:eng
n5:klicovaSlova
cannabinoids; mood stabilizers; antidepressants; Mood disorders
n5:klicoveSlovo
n9:Mood%20disorders n9:antidepressants n9:mood%20stabilizers n9:cannabinoids
n5:kontrolniKodProRIV
[8869AB6C2B48]
n5:mistoVydani
New York
n5:nazevEdiceCisloSvazku
Neuveden
n5:nazevZdroje
Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders
n5:obor
n19:FL
n5:pocetDomacichTvurcuVysledku
1
n5:pocetStranKnihy
337
n5:pocetTvurcuVysledku
1
n5:rokUplatneniVysledku
n7:2013
n5:tvurceVysledku
Fišar, Zdeněk
n5:zamer
n20:MSM0021620849
s:numberOfPages
32
n16:doi
10.1007/978-1-4614-7940-6_6
n22:hasPublisher
Springer-Verlag
n10:isbn
978-1-4614-7939-0
n11:organizacniJednotka
11110