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Statements

Subject Item
n2:RIV%2F00216208%3A11110%2F13%3A10191045%21RIV14-MSM-11110___
rdf:type
n9:Vysledek skos:Concept
rdfs:seeAlso
http://dx.doi.org/10.1093/aje/kwt201
dcterms:description
Several epidemiologic studies have indicated an increased risk of lung cancer among welders. We used the SYNERGY project database to assess welding as a risk factor for developing lung cancer. The database includes data on 15,483 male lung cancer cases and 18,388 male controls from 16 studies in Europe, Canada, China, and New Zealand conducted between 1985 and 2010. Odds ratios and 95 confidence intervals between regular or occasional welding and lung cancer were estimated, with adjustment for smoking, age, study center, and employment in other occupations associated with lung cancer risk. Overall, 568 cases and 427 controls had ever worked as welders and had an odds ratio of developing lung cancer of 1.44 (95 confidence interval: 1.25, 1.67) with the odds ratio increasing for longer duration of welding. In never and light smokers, the odds ratio was 1.96 (95 confidence interval: 1.37, 2.79). The odds ratios were somewhat higher for squamous and small cell lung cancers than for adenocarcinoma. Another 1,994 cases and 1,930 controls had ever worked in occupations with occasional welding. Work in any of these occupations was associated with some elevation of risk, though not as much as observed in regular welders. Our findings lend further support to the hypothesis that welding is associated with an increased risk of lung cancer. Several epidemiologic studies have indicated an increased risk of lung cancer among welders. We used the SYNERGY project database to assess welding as a risk factor for developing lung cancer. The database includes data on 15,483 male lung cancer cases and 18,388 male controls from 16 studies in Europe, Canada, China, and New Zealand conducted between 1985 and 2010. Odds ratios and 95 confidence intervals between regular or occasional welding and lung cancer were estimated, with adjustment for smoking, age, study center, and employment in other occupations associated with lung cancer risk. Overall, 568 cases and 427 controls had ever worked as welders and had an odds ratio of developing lung cancer of 1.44 (95 confidence interval: 1.25, 1.67) with the odds ratio increasing for longer duration of welding. In never and light smokers, the odds ratio was 1.96 (95 confidence interval: 1.37, 2.79). The odds ratios were somewhat higher for squamous and small cell lung cancers than for adenocarcinoma. Another 1,994 cases and 1,930 controls had ever worked in occupations with occasional welding. Work in any of these occupations was associated with some elevation of risk, though not as much as observed in regular welders. Our findings lend further support to the hypothesis that welding is associated with an increased risk of lung cancer.
dcterms:title
Welding and lung cancer in a pooled analysis of case-control studies Welding and lung cancer in a pooled analysis of case-control studies
skos:prefLabel
Welding and lung cancer in a pooled analysis of case-control studies Welding and lung cancer in a pooled analysis of case-control studies
skos:notation
RIV/00216208:11110/13:10191045!RIV14-MSM-11110___
n9:predkladatel
n18:orjk%3A11110
n3:aktivita
n5:I n5:N
n3:aktivity
I, N
n3:cisloPeriodika
10
n3:dodaniDat
n19:2014
n3:domaciTvurceVysledku
n14:4898362
n3:druhVysledku
n8:J
n3:duvernostUdaju
n20:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
117239
n3:idVysledku
RIV/00216208:11110/13:10191045
n3:jazykVysledku
n12:eng
n3:klicovaSlova
welding; occupational exposure; lung cancer; case-control studies
n3:klicoveSlovo
n11:occupational%20exposure n11:welding n11:case-control%20studies n11:lung%20cancer
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[99636DEF61B1]
n3:nazevZdroje
American Journal of Epidemiology
n3:obor
n15:FN
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
46
n3:rokUplatneniVysledku
n19:2013
n3:svazekPeriodika
178
n3:tvurceVysledku
Lissowska, Jolanta Tse, L. A. Gustavsson, Per Zaridze, David Foretova, Lenka Behrens, Thomas Merletti, Franco Olsson, Ann Siemiatycki, Jack Szeszenia-Dabrowska, Neonila Mates, Dana Rudnai, P. Tardon, Adonina Consonni, Dario Van Gelder, Rainer Stuecker, Isabelle Wichmann, H. -Erich Pohlabeln, Hermann Pearce, Neil 't Mannetje, Andrea Marcus, Michael Brueske, Irene Yu, I.T.S. Peters, Susan Ahrens, Wolfgang Caporaso, Neil Joeckel, Karl-Heinz Bencko, Vladimír Kendzia, Benjamin Kromhout, Hans Guida, Florence Landi, Maria Teresa Fabianova, Eleonora Mirabelli, Dario Janout, Vladimir Vermeulen, Roel Richiardi, Lorenzo
n3:wos
000327396800001
s:issn
0002-9262
s:numberOfPages
13
n16:doi
10.1093/aje/kwt201
n7:organizacniJednotka
11110