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Statements

Subject Item
n2:RIV%2F00216208%3A11110%2F12%3A11500%21RIV13-GA0-11110___
rdf:type
skos:Concept n10:Vysledek
rdfs:seeAlso
http://dx.doi.org/10.1007/s00210-012-0800-9
dcterms:description
We investigated the changes in gene expression, receptor number, echocardiography, muscarinic/adrenergic agonist/antagonist changes in heart rate (HR) and HR biorhythm in M-2 KO mice (mice lacking the main cardioinhibitory receptors) in the left ventricle (LV) and right ventricle (RV). We can conclude that although the main cardioinhobitory receptors are not present in the heart, the function is not much affected. We investigated the changes in gene expression, receptor number, echocardiography, muscarinic/adrenergic agonist/antagonist changes in heart rate (HR) and HR biorhythm in M-2 KO mice (mice lacking the main cardioinhibitory receptors) in the left ventricle (LV) and right ventricle (RV). We can conclude that although the main cardioinhobitory receptors are not present in the heart, the function is not much affected.
dcterms:title
Decrease in heart adrenoceptor gene expression and receptor number as compensatory tool for preserved heart function and biological rhythm in M-2 KO animals Decrease in heart adrenoceptor gene expression and receptor number as compensatory tool for preserved heart function and biological rhythm in M-2 KO animals
skos:prefLabel
Decrease in heart adrenoceptor gene expression and receptor number as compensatory tool for preserved heart function and biological rhythm in M-2 KO animals Decrease in heart adrenoceptor gene expression and receptor number as compensatory tool for preserved heart function and biological rhythm in M-2 KO animals
skos:notation
RIV/00216208:11110/12:11500!RIV13-GA0-11110___
n10:predkladatel
n11:orjk%3A11110
n3:aktivita
n17:P
n3:aktivity
P(GA309/09/0406)
n3:cisloPeriodika
12
n3:dodaniDat
n6:2013
n3:domaciTvurceVysledku
n16:5954681 n16:2608871 n16:1666495 n16:7977131 n16:3909824
n3:druhVysledku
n18:J
n3:duvernostUdaju
n14:S
n3:entitaPredkladatele
n13:predkladatel
n3:idSjednocenehoVysledku
129798
n3:idVysledku
RIV/00216208:11110/12:11500
n3:jazykVysledku
n20:eng
n3:klicovaSlova
M-2 muscarinic receptor knockout; Beta-adrenoceptors; biorhytms; echocardiography; telemetry; heart rate; activity; temperature
n3:klicoveSlovo
n4:activity n4:telemetry n4:temperature n4:echocardiography n4:M-2%20muscarinic%20receptor%20knockout n4:biorhytms n4:Beta-adrenoceptors n4:heart%20rate
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[87B19C42200C]
n3:nazevZdroje
Naunyn-Schmiedebergs Archives of Pharmacology
n3:obor
n19:ED
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
5
n3:projekt
n12:GA309%2F09%2F0406
n3:rokUplatneniVysledku
n6:2012
n3:svazekPeriodika
385
n3:tvurceVysledku
Beneš, Jan Farár, Vladimír Mysliveček, Jaromír Nováková, Martina Vařejková, Eva
n3:wos
000310962000002
s:issn
0028-1298
s:numberOfPages
13
n7:organizacniJednotka
11110