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Statements

Subject Item
n2:RIV%2F00216208%3A11110%2F09%3A4023%21RIV10-MSM-11110___
rdf:type
n9:Vysledek skos:Concept
dcterms:description
Nitrite (NO2-) recycling to nitric oxide (NO) is catalysed by a number of enzymes and induces a protective vasodilation effect under hypoxia/ischaemia. In the present work, we tested the in vitro ability of the three NOS (nitric oxide synthase) isoforms to release NO from nitrite under anoxia using electrochemical detection, chemiluminescence and absorption spectroscopy. Nitrite (NO2-) recycling to nitric oxide (NO) is catalysed by a number of enzymes and induces a protective vasodilation effect under hypoxia/ischaemia. In the present work, we tested the in vitro ability of the three NOS (nitric oxide synthase) isoforms to release NO from nitrite under anoxia using electrochemical detection, chemiluminescence and absorption spectroscopy.
dcterms:title
Isoform-specific differences in the nitrite reductase activity of nitric oxide synthases under hypoxia Isoform-specific differences in the nitrite reductase activity of nitric oxide synthases under hypoxia
skos:prefLabel
Isoform-specific differences in the nitrite reductase activity of nitric oxide synthases under hypoxia Isoform-specific differences in the nitrite reductase activity of nitric oxide synthases under hypoxia
skos:notation
RIV/00216208:11110/09:4023!RIV10-MSM-11110___
n3:aktivita
n15:S n15:P n15:Z
n3:aktivity
P(1M0520), S, Z(MSM0021620806)
n3:cisloPeriodika
Part 3
n3:dodaniDat
n8:2010
n3:domaciTvurceVysledku
n12:4688678 n12:4768620
n3:druhVysledku
n13:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
320496
n3:idVysledku
RIV/00216208:11110/09:4023
n3:jazykVysledku
n10:eng
n3:klicovaSlova
chemiluminescence; hypoxia; microvascular endothelial cell; nitric oxide synthase (NOS); nitrite reduction; NO electrode; vivo ischemia-reperfusion; endothelial no synthase; xanthine oxidoreductase; crystal-structure; reduces nitrite; heme domain; blood-flow; brain; tetrahydrobiopterin; generation
n3:klicoveSlovo
n6:vivo%20ischemia-reperfusion n6:endothelial%20no%20synthase n6:crystal-structure n6:NO%20electrode n6:brain n6:reduces%20nitrite n6:xanthine%20oxidoreductase n6:hypoxia n6:generation n6:microvascular%20endothelial%20cell n6:heme%20domain n6:chemiluminescence n6:nitric%20oxide%20synthase%20%28NOS%29 n6:nitrite%20reduction n6:tetrahydrobiopterin n6:blood-flow
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[26A4183CE9AA]
n3:nazevZdroje
Biochemical Journal
n3:obor
n4:CE
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
5
n3:projekt
n19:1M0520
n3:rokUplatneniVysledku
n8:2009
n3:svazekPeriodika
418
n3:tvurceVysledku
Mutus, B. Mikula, Ivan Slama-Schwok, A. Durocher, S. Martásek, Pavel
n3:wos
000264145300019
n3:zamer
n16:MSM0021620806
s:issn
0264-6021
s:numberOfPages
10
n14:organizacniJednotka
11110