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Statements

Subject Item
n2:RIV%2F00209805%3A_____%2F13%3A%230000599%21RIV15-MSM-00209805
rdf:type
n3:Vysledek skos:Concept
rdfs:seeAlso
http://www.epj-conferences.org/articles/epjconf/pdf/2013/06/epjconf_efm2013_01060.pdf
dcterms:description
Positron Emission Tomography (PET) is a convenient method for measurement of aerosol deposition in complex models of lungs. It allows not only the evaluation of regional deposition characteristics but also precisely detects deposition hot spots. The method is based on a detection of a pair of annihilation photons moving in opposite directions as a result of positron – electron interaction after the positron emission decay of a suitable radioisotope. Liquid di(2-ethylhexyl) sebacate (DEHS) particles tagged with fluorine-18 as a radioactive tracer were generated by condensation monodisperse aerosol generator. Aerosol deposition was measured for three different inhalation flowrates and for two sizes of particles. Combination of PET with Computed Tomography (CT) in one device allowed precise localisation of particular segments of the model. The results proved correlation of deposition efficiency with Stokes number, which means that the main deposition mechanism is inertial impaction. As a next task the methodology for tagging the solid aerosol particles with radioactive tracer will be developed and deposition of porous and fiber aerosols will be measured. Positron Emission Tomography (PET) is a convenient method for measurement of aerosol deposition in complex models of lungs. It allows not only the evaluation of regional deposition characteristics but also precisely detects deposition hot spots. The method is based on a detection of a pair of annihilation photons moving in opposite directions as a result of positron – electron interaction after the positron emission decay of a suitable radioisotope. Liquid di(2-ethylhexyl) sebacate (DEHS) particles tagged with fluorine-18 as a radioactive tracer were generated by condensation monodisperse aerosol generator. Aerosol deposition was measured for three different inhalation flowrates and for two sizes of particles. Combination of PET with Computed Tomography (CT) in one device allowed precise localisation of particular segments of the model. The results proved correlation of deposition efficiency with Stokes number, which means that the main deposition mechanism is inertial impaction. As a next task the methodology for tagging the solid aerosol particles with radioactive tracer will be developed and deposition of porous and fiber aerosols will be measured.
dcterms:title
Application of Positron Emission Tomography to aerosol transport research in a model of human lungs Application of Positron Emission Tomography to aerosol transport research in a model of human lungs
skos:prefLabel
Application of Positron Emission Tomography to aerosol transport research in a model of human lungs Application of Positron Emission Tomography to aerosol transport research in a model of human lungs
skos:notation
RIV/00209805:_____/13:#0000599!RIV15-MSM-00209805
n4:aktivita
n19:S n19:P
n4:aktivity
P(ED2.1.00/03.0101), P(GAP105/11/1339), P(ME09030), S
n4:dodaniDat
n17:2015
n4:domaciTvurceVysledku
n18:7678037
n4:druhVysledku
n21:D
n4:duvernostUdaju
n14:S
n4:entitaPredkladatele
n11:predkladatel
n4:idSjednocenehoVysledku
123369
n4:idVysledku
RIV/00209805:_____/13:#0000599
n4:jazykVysledku
n22:eng
n4:klicovaSlova
aerosol transport; positron emission tomography; human lung model
n4:klicoveSlovo
n5:aerosol%20transport n5:human%20lung%20model n5:positron%20emission%20tomography
n4:kontrolniKodProRIV
[70FF387F066C]
n4:mistoKonaniAkce
Hradec Králové
n4:nazevZdroje
EPJ Web of Conferences
n4:obor
n15:FP
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
4
n4:projekt
n10:ME09030 n10:GAP105%2F11%2F1339 n10:ED2.1.00%2F03.0101
n4:rokUplatneniVysledku
n17:2013
n4:tvurceVysledku
Adam, Jan
n4:typAkce
n20:EUR
n4:wos
000319932200060
n4:zahajeniAkce
2013-01-01+01:00
s:issn
2100-014X
s:numberOfPages
4
n9:doi
10.1051/epjconf/20134501060
n7:hasPublisher
E D P SCIENCES
n16:isbn
978-80-7372-912-7